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FAM90A1 family with sequence similarity 90 member A1 [ Homo sapiens (human) ]

Gene ID: 55138, updated on 11-Jun-2021

Summary

Official Symbol
FAM90A1provided by HGNC
Official Full Name
family with sequence similarity 90 member A1provided by HGNC
Primary source
HGNC:HGNC:25526
See related
Ensembl:ENSG00000171847 MIM:613041
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
FAM90A1 belongs to subfamily I of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]).[supplied by OMIM, Oct 2009]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See FAM90A1 in Genome Data Viewer
Location:
12p13.31
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (8221260..8227618, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8373856..8380214, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene zinc finger protein 705A Neighboring gene family with sequence similarity 66 member C Neighboring gene defensin beta 109F (pseudogene) Neighboring gene ALG1 like 10, pseudogene Neighboring gene family with sequence similarity 86, member A pseudogene Neighboring gene long intergenic non-protein coding RNA 2449

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10408

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319982.2NP_001306911.1  protein FAM90A1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC092111, AK001270, DA088850
    Consensus CDS
    CCDS31738.1
    UniProtKB/Swiss-Prot
    Q86YD7
    Related
    ENSP00000307798.6, ENST00000307435.10
    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family
  2. NM_018088.3NP_060558.3  protein FAM90A1

    See identical proteins and their annotated locations for NP_060558.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC092111, BC042608, DA088850
    Consensus CDS
    CCDS31738.1
    UniProtKB/Swiss-Prot
    Q86YD7
    Related
    ENSP00000445418.1, ENST00000538603.6
    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    8221260..8227618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019547.1XP_016875036.1  protein FAM90A1 isoform X2

    UniProtKB/Swiss-Prot
    Q86YD7
    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family
  2. XM_011520719.1XP_011519021.1  protein FAM90A1 isoform X2

    See identical proteins and their annotated locations for XP_011519021.1

    UniProtKB/Swiss-Prot
    Q86YD7
    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family
  3. XM_024449030.1XP_024304798.1  protein FAM90A1 isoform X2

    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family
  4. XM_024449029.1XP_024304797.1  protein FAM90A1 isoform X2

    Conserved Domains (2) summary
    pfam15288
    Location:4176
    zf-CCHC_6; Zinc knuckle
    cl26464
    Location:25371
    Atrophin-1; Atrophin-1 family
  5. XM_006719097.3XP_006719160.1  protein FAM90A1 isoform X1

    Conserved Domains (1) summary
    pfam15288
    Location:6099
    zf-CCHC_6; Zinc knuckle
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