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TTC38 tetratricopeptide repeat domain 38 [ Homo sapiens (human) ]

Gene ID: 55020, updated on 4-Dec-2022

Summary

Official Symbol
TTC38provided by HGNC
Official Full Name
tetratricopeptide repeat domain 38provided by HGNC
Primary source
HGNC:HGNC:26082
See related
Ensembl:ENSG00000075234 AllianceGenome:HGNC:26082
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LL22NC03-5H6.5
Summary
Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney (RPKM 26.4), small intestine (RPKM 22.0) and 25 other tissues See more
Orthologs
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Genomic context

See TTC38 in Genome Data Viewer
Location:
22q13.31
Exon count:
17
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (46268008..46294008)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (46752708..46778705)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (46663905..46689905)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene cysteine rich DPF motif domain containing 1 Neighboring gene polycystin family receptor for egg jelly Neighboring gene GTSE1 divergent transcript Neighboring gene G2 and S-phase expressed 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20699

General protein information

Preferred Names
tetratricopeptide repeat protein 38
Names
TPR repeat protein 38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017931.4NP_060401.3  tetratricopeptide repeat protein 38

    Status: VALIDATED

    Source sequence(s)
    Z93024
    Consensus CDS
    CCDS43030.1
    UniProtKB/Swiss-Prot
    Q9NWP8
    Related
    ENSP00000370419.3, ENST00000381031.8
    Conserved Domains (1) summary
    cd05804
    Location:60423
    StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been speculated ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    46268008..46294008
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441439.1XP_047297395.1  tetratricopeptide repeat protein 38 isoform X3

  2. XM_047441440.1XP_047297396.1  tetratricopeptide repeat protein 38 isoform X4

    Related
    ENSP00000406604.1, ENST00000422713.1
  3. XM_011530260.4XP_011528562.1  tetratricopeptide repeat protein 38 isoform X2

    Related
    ENSP00000410095.1, ENST00000421359.5
    Conserved Domains (1) summary
    cd05804
    Location:60206
    StaR_like; StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been ...
  4. XM_047441438.1XP_047297394.1  tetratricopeptide repeat protein 38 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    46752708..46778705
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)