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TUG1 taurine up-regulated 1 [ Homo sapiens (human) ]

Gene ID: 55000, updated on 5-Jul-2020

Summary

Official Symbol
TUG1provided by HGNC
Official Full Name
taurine up-regulated 1provided by HGNC
Primary source
HGNC:HGNC:26066
See related
Ensembl:ENSG00000253352 MIM:614971
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TI-227H; LINC00080; NCRNA00080
Summary
This gene produces a long non-coding RNA that interacts with the Polycomb repressor complex and functions in the epigenetic regulation of transcription. This RNA promotes cell proliferation and is upregulated in tumor cells. It may act as a sponge for microRNAs. The homologous mouse gene is required for differentiation of retina. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2017]
Expression
Ubiquitous expression in testis (RPKM 36.1), endometrium (RPKM 31.7) and 25 other tissues See more
Orthologs

Genomic context

See TUG1 in Genome Data Viewer
Location:
22q12.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (30969211..30979395)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (31365634..31375381)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein 2 Neighboring gene uncharacterized LOC107985544 Neighboring gene eukaryotic translation initiation factor 4H pseudogene 2 Neighboring gene MORC2 antisense RNA 1 Neighboring gene MORC family CW-type zinc finger 2 Neighboring gene RNA, 7SL, cytoplasmic 633, pseudogene Neighboring gene smoothelin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • TUG1 noncoding RNA
  • long intergenic non-protein coding RNA 80
  • taurine up-regulated 1 (non-protein coding)
  • taurine upregulated gene 1

Clone Names

  • FLJ20618, MGC46067

Gene Ontology Provided by GOA

Process Evidence Code Pubs
regulation of eye photoreceptor cell development IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002323.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
  2. NR_110492.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
  3. NR_110493.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
    Related
    ENST00000644773.1
  4. NR_152867.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
    Related
    ENST00000646496.1
  5. NR_152868.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
  6. NR_152869.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
  7. NR_152870.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542
    Related
    ENST00000643071.1
  8. NR_152871.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC004542

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    30969211..30979395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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