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C1orf159 chromosome 1 open reading frame 159 [ Homo sapiens (human) ]

Gene ID: 54991, updated on 1-Aug-2020

Summary

Official Symbol
C1orf159provided by HGNC
Official Full Name
chromosome 1 open reading frame 159provided by HGNC
Primary source
HGNC:HGNC:26062
See related
Ensembl:ENSG00000131591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 2.6), skin (RPKM 1.2) and 24 other tissues See more
Orthologs

Genomic context

See C1orf159 in Genome Data Viewer
Location:
1p36.33
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (1081823..1116089, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1017198..1051736, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378948 Neighboring gene conserved acetylation island sequence 30 enhancer Neighboring gene ring finger protein 223 Neighboring gene Sharpr-MPRA regulatory region 13538 Neighboring gene CRISPRi-validated cis-regulatory element chr1.97 Neighboring gene long intergenic non-protein coding RNA 1342

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20584, FLJ21143, FLJ36119

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein C1orf159

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330306.2NP_001317235.1  uncharacterized protein C1orf159 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL390719
    Consensus CDS
    CCDS81250.1
    UniProtKB/Swiss-Prot
    Q96HA4
    Related
    ENSP00000368644.1, ENST00000379339.5
  2. NM_001363525.2NP_001350454.1  uncharacterized protein C1orf159 isoform 3 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AL390719
    Consensus CDS
    CCDS85917.1
    Related
    ENSP00000368624.1, ENST00000379320.5
    Conserved Domains (1) summary
    pfam14946
    Location:23167
    DUF4501; Domain of unknown function (DUF4501)
  3. NM_017891.5NP_060361.4  uncharacterized protein C1orf159 isoform 2 precursor

    See identical proteins and their annotated locations for NP_060361.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AK000591, BE280321, BM974309
    Consensus CDS
    CCDS7.2
    UniProtKB/Swiss-Prot
    Q96HA4
    UniProtKB/TrEMBL
    A0A024R082
    Related
    ENSP00000400736.2, ENST00000421241.6
    Conserved Domains (1) summary
    pfam14946
    Location:23198
    DUF4501; Domain of unknown function (DUF4501)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    1081823..1116089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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