U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TRNAU1AP tRNA selenocysteine 1 associated protein 1 [ Homo sapiens (human) ]

Gene ID: 54952, updated on 9-Jun-2025
Official Symbol
TRNAU1APprovided by HGNC
Official Full Name
tRNA selenocysteine 1 associated protein 1provided by HGNC
Primary source
HGNC:HGNC:30813
See related
Ensembl:ENSG00000180098 MIM:619597; AllianceGenome:HGNC:30813
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SECP43; PRO1902; TRSPAP1
Summary
Enables RNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Ubiquitous expression in lymph node (RPKM 5.3), urinary bladder (RPKM 4.9) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table
See TRNAU1AP in Genome Data Viewer
Location:
1p35.3
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (28553085..28578545)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (28395040..28420501)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (28879597..28905057)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene regulator of chromosome condensation 1 Neighboring gene small nucleolar RNA U13 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:28844515-28845366 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:28845367-28846217 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:28850571-28851072 Neighboring gene peroxiredoxin 3 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:28866050-28866550 Neighboring gene Sharpr-MPRA regulatory region 11844 Neighboring gene Sharpr-MPRA regulatory region 11894 Neighboring gene small nucleolar RNA, C/D box 99 Neighboring gene small nucleolar RNA host gene 12 Neighboring gene small nucleolar RNA, H/ACA box 61

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ20503

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in selenocysteine incorporation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in selenocysteine incorporation IEA
Inferred from Electronic Annotation
more info
 
involved_in selenocysteine incorporation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
tRNA selenocysteine 1-associated protein 1
Names
tRNA selenocysteine associated protein (SECP43)
tRNA selenocysteine-associated protein 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017846.5NP_060316.1  tRNA selenocysteine 1-associated protein 1

    See identical proteins and their annotated locations for NP_060316.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    BC000680, BI602122, BQ014404
    Consensus CDS
    CCDS324.1
    UniProtKB/Swiss-Prot
    Q86SU7, Q9NX07
    Related
    ENSP00000362936.3, ENST00000373830.4
    Conserved Domains (3) summary
    pfam17654
    Location:205284
    Trnau1ap; Selenocysteine tRNA 1 associated proteins
    cd12610
    Location:487
    RRM1_SECp43; RNA recognition motif 1 (RRM1) found in tRNA selenocysteine-associated protein 1 (SECp43)
    cd12612
    Location:95176
    RRM2_SECp43; RNA recognition motif 2 (RRM2) found in tRNA selenocysteine-associated protein 1 (SECp43)

RNA

  1. NR_003109.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC000680, BC039879, BI602122, BQ014404

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    28553085..28578545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    28395040..28420501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)