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UHRF1BP1 UHRF1 binding protein 1 [ Homo sapiens (human) ]

Gene ID: 54887, updated on 1-Jun-2020

Summary

Official Symbol
UHRF1BP1provided by HGNC
Official Full Name
UHRF1 binding protein 1provided by HGNC
Primary source
HGNC:HGNC:21216
See related
Ensembl:ENSG00000065060
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ICBP90; C6orf107; dJ349A12.1
Expression
Broad expression in testis (RPKM 8.7), bone marrow (RPKM 5.2) and 25 other tissues See more
Orthologs

Genomic context

See UHRF1BP1 in Genome Data Viewer
Location:
6p21.31
Exon count:
21
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (34792083..34877514)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (34759794..34845291)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S10 pseudogene 13 Neighboring gene small nuclear ribonucleoprotein polypeptide C Neighboring gene RNY3 pseudogene 15 Neighboring gene TATA-box binding protein associated factor 11 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1A Neighboring gene heat shock protein family E (Hsp10) member 1 pseudogene 11 Neighboring gene t-complex 11

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
NHGRI GWA Catalog
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
NHGRI GWA Catalog
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
NHGRI GWA Catalog
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20302

Gene Ontology Provided by GOA

Function Evidence Code Pubs
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase binding IPI
Inferred from Physical Interaction
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
UHRF1-binding protein 1
Names
ICBP90 binding protein 1
UHRF1 (ICBP90) binding protein 1
ubiquitin-like containing PHD and RING finger domains 1-binding protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017754.4NP_060224.3  UHRF1-binding protein 1

    See identical proteins and their annotated locations for NP_060224.3

    Status: VALIDATED

    Source sequence(s)
    AA287944, AB126777, AL033520, DB636320
    Consensus CDS
    CCDS43455.1
    UniProtKB/Swiss-Prot
    Q6BDS2
    Related
    ENSP00000192788.5, ENST00000192788.6
    Conserved Domains (1) summary
    pfam12624
    Location:389
    Chorein_N; N-terminal region of Chorein or VPS13

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    34792083..34877514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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