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AHI1 Abelson helper integration site 1 [ Homo sapiens (human) ]

Gene ID: 54806, updated on 10-Dec-2024

Summary

Official Symbol
AHI1provided by HGNC
Official Full Name
Abelson helper integration site 1provided by HGNC
Primary source
HGNC:HGNC:21575
See related
Ensembl:ENSG00000135541 MIM:608894; AllianceGenome:HGNC:21575
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ORF1; AHI-1; JBTS3; dJ71N10.1
Summary
This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Expression
Broad expression in testis (RPKM 9.3), adrenal (RPKM 5.6) and 25 other tissues See more
Orthologs
NEW
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Genomic context

See AHI1 in Genome Data Viewer
Location:
6q23.3
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (135283532..135497740, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (136471820..136685994, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (135604670..135818878, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25103 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25104 Neighboring gene MYB proto-oncogene, transcription factor Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:135570900-135572099 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:135573042-135573542 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:135573543-135574043 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:135577907-135579106 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:135585007-135585209 Neighboring gene microRNA 548a-2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:135591948-135592842 Neighboring gene VISTA enhancer hs1351 Neighboring gene uncharacterized LOC124901407 Neighboring gene CRISPRi-validated MYB cis-regulatory element XLOC_042889 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25105 Neighboring gene Sharpr-MPRA regulatory region 12318 Neighboring gene beta-transducin repeat containing E3 ubiquitin protein ligase pseudogene 1 Neighboring gene MPRA-validated peak6137 silencer Neighboring gene MPRA-validated peak6138 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25106 Neighboring gene MPRA-validated peak6140 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25107 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17569 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17570 Neighboring gene AHI1 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17571 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:135921214-135922413 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene 73 Neighboring gene long intergenic non-protein coding RNA 2524

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Joubert syndrome 3
MedGen: C1837713 OMIM: 608629 GeneReviews: Joubert Syndrome
Compare labs

EBI GWAS Catalog

Description
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ14023, FLJ20069, DKFZp686J1653

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in central nervous system development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cloaca development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in heart looping ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in hindbrain development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in morphogenesis of a polarized epithelium ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in otic vesicle development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in photoreceptor cell outer segment organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of polarized epithelial cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of receptor internalization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in pronephric nephron tubule morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein localization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of behavior ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in retina layer formation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in specification of axis polarity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of MKS complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in centriole ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in non-motile cilium ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
jouberin
Names
abelson helper integration site 1 protein homolog
contatins SH3 and WD40 domains

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008643.2 RefSeqGene

    Range
    5026..219234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134830.2NP_001128302.1  jouberin isoform a

    See identical proteins and their annotated locations for NP_001128302.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5', compared to variant 1. Variants 1-3 and 5 all encode the same isoform (a).
    Source sequence(s)
    AI300295, AJ459824, AL023693
    Consensus CDS
    CCDS47483.1
    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Related
    ENSP00000356774.4, ENST00000367800.8
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001134831.2NP_001128303.1  jouberin isoform a

    See identical proteins and their annotated locations for NP_001128303.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 and 5 all encode the same isoform (a).
    Source sequence(s)
    AI300295, AJ459824, AL023693, AY133243
    Consensus CDS
    CCDS47483.1
    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Related
    ENSP00000265602.6, ENST00000265602.11
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. NM_001134832.2NP_001128304.1  jouberin isoform b

    See identical proteins and their annotated locations for NP_001128304.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and the 3' coding region, compared to variant 1. The resulting isoform (b) contains a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AJ459824, AJ459825
    Consensus CDS
    CCDS47484.1
    UniProtKB/TrEMBL
    A0A7P0TA48
    Related
    ENSP00000322478.6, ENST00000327035.10
    Conserved Domains (3) summary
    COG2319
    Location:597919
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. NM_001350503.2NP_001337432.1  jouberin isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 1-3, encodes isoform a.
    Source sequence(s)
    AL023693, AL049552, AL133544
    Consensus CDS
    CCDS47483.1
    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Related
    ENSP00000504965.1, ENST00000681841.1
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. NM_001350504.2NP_001337433.1  jouberin isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) encodes isoform c.
    Source sequence(s)
    AL023693, AL049552, AL133544
    Consensus CDS
    CCDS94006.1
    UniProtKB/TrEMBL
    A0A7P0T959, A0A7P0T9I7
    Related
    ENSP00000505502.1, ENST00000679925.1
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. NM_017651.5NP_060121.3  jouberin isoform a

    See identical proteins and their annotated locations for NP_060121.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5', compared to variant 1. Variants 1-3 and 5 all encode the same isoform (a).
    Source sequence(s)
    AI300295, AJ459824, AL023693
    Consensus CDS
    CCDS47483.1
    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Related
    ENSP00000388650.2, ENST00000457866.6
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    135283532..135497740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047418943.1XP_047274899.1  jouberin isoform X4

    UniProtKB/TrEMBL
    A0A7P0T959, A0A7P0T9I7
    Related
    ENSP00000504890.1, ENST00000679742.1
  2. XM_011535911.4XP_011534213.1  jouberin isoform X1

    See identical proteins and their annotated locations for XP_011534213.1

    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_047418942.1XP_047274898.1  jouberin isoform X4

    UniProtKB/TrEMBL
    A0A7P0T959, A0A7P0T9I7
  4. XM_011535910.4XP_011534212.1  jouberin isoform X1

    See identical proteins and their annotated locations for XP_011534212.1

    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
    Related
    ENSP00000506005.1, ENST00000681522.1
    Conserved Domains (3) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_047418940.1XP_047274896.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
    Related
    ENSP00000505663.1, ENST00000679943.1
  6. XM_047418939.1XP_047274895.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
  7. XM_047418941.1XP_047274897.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
  8. XM_017010979.3XP_016866468.1  jouberin isoform X2

    UniProtKB/TrEMBL
    A0A7P0T7Z8, A0A7P0T9I7
    Related
    ENSP00000504895.1, ENST00000681670.1
    Conserved Domains (4) summary
    cd11812
    Location:10551106
    SH3_AHI-1; Src Homology 3 domain of Abelson helper integration site-1 (AHI-1)
    COG2319
    Location:597919
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  9. XM_024446480.2XP_024302248.1  jouberin isoform X5

    UniProtKB/TrEMBL
    A0A7P0TA48
    Related
    ENSP00000506009.1, ENST00000680184.1
    Conserved Domains (2) summary
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  10. XM_047418944.1XP_047274900.1  jouberin isoform X6

    UniProtKB/TrEMBL
    A0A7P0T9Q2, A0A7P0TA48
    Related
    ENSP00000506261.1, ENST00000679622.1
  11. XM_047418945.1XP_047274901.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48
  12. XM_017010984.3XP_016866473.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48
    Conserved Domains (3) summary
    COG2319
    Location:597919
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:612652
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:611907
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  13. XM_047418946.1XP_047274902.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48
    Related
    ENST00000681945.1

RNA

  1. XR_001743480.3 RNA Sequence

  2. XR_007059277.1 RNA Sequence

    Related
    ENST00000531788.5
  3. XR_007059276.1 RNA Sequence

    Related
    ENST00000681488.1
  4. XR_007059278.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    136471820..136685994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054355740.1XP_054211715.1  jouberin isoform X4

    UniProtKB/TrEMBL
    A0A7P0T959, A0A7P0T9I7
  2. XM_054355734.1XP_054211709.1  jouberin isoform X1

    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
  3. XM_054355739.1XP_054211714.1  jouberin isoform X4

    UniProtKB/TrEMBL
    A0A7P0T959, A0A7P0T9I7
  4. XM_054355733.1XP_054211708.1  jouberin isoform X1

    UniProtKB/Swiss-Prot
    E1P584, Q4FD35, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8N157, Q8NDX0, Q9H0H2
    UniProtKB/TrEMBL
    A0A7P0T8H6
  5. XM_054355737.1XP_054211712.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
  6. XM_054355736.1XP_054211711.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
  7. XM_054355738.1XP_054211713.1  jouberin isoform X3

    UniProtKB/TrEMBL
    A0A7P0T9I7, A0A7P0T9M6
  8. XM_054355735.1XP_054211710.1  jouberin isoform X2

    UniProtKB/TrEMBL
    A0A7P0T7Z8, A0A7P0T9I7
  9. XM_054355741.1XP_054211716.1  jouberin isoform X5

    UniProtKB/TrEMBL
    A0A7P0TA48
  10. XM_054355742.1XP_054211717.1  jouberin isoform X6

    UniProtKB/TrEMBL
    A0A7P0T9Q2, A0A7P0TA48
  11. XM_054355743.1XP_054211718.1  jouberin isoform X8

    UniProtKB/TrEMBL
    A0A7P0TA48
  12. XM_054355745.1XP_054211720.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48
  13. XM_054355744.1XP_054211719.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48
  14. XM_054355746.1XP_054211721.1  jouberin isoform X7

    UniProtKB/TrEMBL
    A0A7P0TA48

RNA

  1. XR_008487350.1 RNA Sequence

  2. XR_008487352.1 RNA Sequence

  3. XR_008487351.1 RNA Sequence

  4. XR_008487353.1 RNA Sequence