Format

Send to:

Choose Destination

TOMM7 translocase of outer mitochondrial membrane 7 [ Homo sapiens (human) ]

Gene ID: 54543, updated on 1-Aug-2020

Summary

Official Symbol
TOMM7provided by HGNC
Official Full Name
translocase of outer mitochondrial membrane 7provided by HGNC
Primary source
HGNC:HGNC:21648
See related
Ensembl:ENSG00000196683 MIM:607980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TOM7
Summary
This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]
Expression
Ubiquitous expression in ovary (RPKM 141.3), fat (RPKM 120.2) and 25 other tissues See more
Orthologs

Genomic context

See TOMM7 in Genome Data Viewer
Location:
7p15.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (22812974..22822849, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (22852251..22862471, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene MT-CYB pseudogene 42 Neighboring gene ribosomal protein S26 pseudogene 32 Neighboring gene uncharacterized LOC112267993 Neighboring gene small nucleolar RNA host gene 26 Neighboring gene small nucleolar RNA, C/D box 93

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein transmembrane transporter activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane TAS
Traceable Author Statement
more info
 
mitochondrial outer membrane translocase complex IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane translocase complex TAS
Traceable Author Statement
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
mitochondrial import receptor subunit TOM7 homolog
Names
translocase of outer membrane 7 kDa subunit homolog
translocase of outer mitochondrial membrane 7 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019059.5NP_061932.1  mitochondrial import receptor subunit TOM7 homolog

    See identical proteins and their annotated locations for NP_061932.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and is the protein-coding variant.
    Source sequence(s)
    AC005682
    Consensus CDS
    CCDS5376.1
    UniProtKB/Swiss-Prot
    Q9P0U1
    UniProtKB/TrEMBL
    Q75MR5
    Related
    ENSP00000351214.4, ENST00000358435.8
    Conserved Domains (1) summary
    pfam08038
    Location:953
    Tom7; TOM7 family

RNA

  1. NR_168014.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005682
  2. NR_168015.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005682

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    22812974..22822849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center