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REV3L REV3 like, DNA directed polymerase zeta catalytic subunit [ Bos taurus (domestic cattle) ]

Gene ID: 517422, updated on 17-Aug-2024

Summary

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Official Symbol
REV3Lprovided by VGNC
Official Full Name
REV3 like, DNA directed polymerase zeta catalytic subunitprovided by VGNC
Primary source
VGNC:VGNC:33883
See related
BGD:BT20716; Ensembl:ENSBTAG00000010760
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (38930097..39108208)

Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene TRAF3 interacting protein 2 Neighboring gene gametogenetin Neighboring gene ribosomal protein L23a pseudogene Neighboring gene microRNA mir-6536-2 Neighboring gene microRNA mir-6536-1 Neighboring gene uncharacterized LOC132346162 Neighboring gene uncharacterized LOC132346161 Neighboring gene major facilitator superfamily domain containing 4B Neighboring gene solute carrier family 16 member 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in error-prone translesion synthesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of zeta DNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase zeta catalytic subunit
Names
REV3-like, catalytic subunit of DNA polymerase zeta
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
NP_001193101.2
XP_024852357.1
XP_024852358.1
XP_024852359.1
XP_024852360.1
XP_059745669.1
XP_059745670.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206172.2 → NP_001193101.2  DNA polymerase zeta catalytic subunit

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000009
    UniProtKB/TrEMBL
    E1BPY8
    Related
    ENSBTAP00000053310.3, ENSBTAT00000060948.4
    Conserved Domains (6) summary
    cd05778
    Location:2297 → 2535
    DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase
    cd05534
    Location:2561 → 3009
    POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...
    pfam07964
    Location:1176 → 1371
    Red1; Rec10 / Red1
    pfam14260
    Location:3045 → 3112
    zf-C4pol; C4-type zinc-finger of DNA polymerase delta
    pfam15735
    Location:747 → 1134
    DUF4683; Domain of unknown function (DUF4683)
    cl10023
    Location:17 → 182
    POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    38930097..39108208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024996589.2 → XP_024852357.1  DNA polymerase zeta catalytic subunit isoform X1

    Conserved Domains (6) summary
    cd05778
    Location:2298 → 2536
    DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase
    cd05534
    Location:2562 → 3010
    POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...
    pfam07964
    Location:1177 → 1372
    Red1; Rec10 / Red1
    pfam14260
    Location:3046 → 3113
    zf-C4pol; C4-type zinc-finger of DNA polymerase delta
    pfam15735
    Location:748 → 1135
    DUF4683; Domain of unknown function (DUF4683)
    cl10023
    Location:17 → 182
    POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...

  2. XM_024996590.2 → XP_024852358.1  DNA polymerase zeta catalytic subunit isoform X2

    Conserved Domains (6) summary
    cd05778
    Location:2292 → 2530
    DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase
    cd05534
    Location:2556 → 3004
    POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...
    pfam07964
    Location:1171 → 1366
    Red1; Rec10 / Red1
    pfam14260
    Location:3040 → 3107
    zf-C4pol; C4-type zinc-finger of DNA polymerase delta
    pfam15735
    Location:742 → 1129
    DUF4683; Domain of unknown function (DUF4683)
    cl10023
    Location:17 → 182
    POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...

  3. XM_059889687.1 → XP_059745670.1  DNA polymerase zeta catalytic subunit isoform X4

  4. XM_024996591.2 → XP_024852359.1  DNA polymerase zeta catalytic subunit isoform X3

    Conserved Domains (6) summary
    cd05778
    Location:2220 → 2458
    DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase
    cd05534
    Location:2484 → 2932
    POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...
    pfam03104
    Location:22 → 111
    DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain
    pfam07964
    Location:1099 → 1294
    Red1; Rec10 / Red1
    pfam14260
    Location:2968 → 3035
    zf-C4pol; C4-type zinc-finger of DNA polymerase delta
    pfam15735
    Location:670 → 1057
    DUF4683; Domain of unknown function (DUF4683)

  5. XM_059889686.1 → XP_059745669.1  DNA polymerase zeta catalytic subunit isoform X3

  6. XM_024996592.2 → XP_024852360.1  DNA polymerase zeta catalytic subunit isoform X3

    Conserved Domains (6) summary
    cd05778
    Location:2220 → 2458
    DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase
    cd05534
    Location:2484 → 2932
    POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...
    pfam03104
    Location:22 → 111
    DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain
    pfam07964
    Location:1099 → 1294
    Red1; Rec10 / Red1
    pfam14260
    Location:2968 → 3035
    zf-C4pol; C4-type zinc-finger of DNA polymerase delta
    pfam15735
    Location:670 → 1057
    DUF4683; Domain of unknown function (DUF4683)
Nucleotide Protein Strain
Heading Accession and Version

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