ERCC4 ERCC excision repair 4, endonuclease catalytic subunit [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ERCC4provided by VGNC
Official Full Name: ERCC excision repair 4, endonuclease catalytic subunitprovided by VGNC
Primary source: VGNC:VGNC:28571
See related: Ensembl:ENSBTAG00000021773
Gene type: protein coding
RefSeq status: INFERRED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	25	NC_037352.1 (12833435..12874714)

Chromosome 25 - NC_037352.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables damaged DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables single-stranded DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables single-stranded DNA endodeoxyribonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nucleotide-excision repair involved in interstrand cross-link repair	IEA Inferred from Electronic Annotation more info	PubMed
involved_in resolution of meiotic recombination intermediates	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of nucleotide-excision repair factor 1 complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA repair endonuclease XPF

Names: excision repair cross-complementing rodent repair deficiency, complementation group 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001205360.1 → NP_001192289.1 DNA repair endonuclease XPF

See identical proteins and their annotated locations for NP_001192289.1

Status: INFERRED

Source sequence(s)

NKLS02000025

UniProtKB/TrEMBL

A0AAA9SBB1, E1BKV9

Related

ENSBTAP00000043645.3, ENSBTAT00000046336.5

Conserved Domains (2) summary

TIGR00596
Location:97 → 907

rad1; DNA repair protein (rad1)

pfam02732
Location:686 → 816

ERCC4; ERCC4 domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

Range

12833435..12874714

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024984853.2 → XP_024840621.1 DNA repair endonuclease XPF isoform X1

UniProtKB/TrEMBL

A0AAA9TM75

Conserved Domains (1) summary

cl27383
Location:1 → 726

ERCC4; ERCC4 domain