Format

Send to:

Choose Destination

CCZ1 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated [ Homo sapiens (human) ]

Gene ID: 51622, updated on 8-Aug-2021

Summary

Official Symbol
CCZ1provided by HGNC
Official Full Name
CCZ1 homolog, vacuolar protein trafficking and biogenesis associatedprovided by HGNC
Primary source
HGNC:HGNC:21691
See related
Ensembl:ENSG00000122674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCZ1A; CGI-43; C7orf28A; H_DJ1163J12.2
Expression
Ubiquitous expression in adrenal (RPKM 39.9), urinary bladder (RPKM 31.0) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See CCZ1 in Genome Data Viewer
Location:
7p22.1
Exon count:
15
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (5898733..5926550)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (5938364..5966181)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene zinc finger protein 815, pseudogene Neighboring gene RNA, 7SL, cytoplasmic 556, pseudogene Neighboring gene oncomodulin Neighboring gene nonconserved acetylation island sequence 61 enhancer Neighboring gene uncharacterized LOC107986694 Neighboring gene radial spoke head 10 homolog B Neighboring gene PMS1 homolog 2, mismatch repair system component Neighboring gene small nucleolar RNA, H/ACA box 80D Neighboring gene aminoacyl tRNA synthetase complex interacting multifunctional protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vacuolar fusion protein CCZ1 homolog
Names
CCZ1 vacuolar protein trafficking and biogenesis associated homolog
H_NH0577018.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015622.6NP_056437.4  vacuolar fusion protein CCZ1 homolog

    See identical proteins and their annotated locations for NP_056437.4

    Status: VALIDATED

    Source sequence(s)
    AC004983, AF151801, BC067810, BI546694, CN310516
    Consensus CDS
    CCDS34597.1
    UniProtKB/Swiss-Prot
    P86790, P86791
    Related
    ENSP00000325681.6, ENST00000325974.9
    Conserved Domains (1) summary
    pfam08217
    Location:27479
    DUF1712; Fungal domain of unknown function (DUF1712)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    5898733..5926550
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center