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COL11A2 collagen type XI alpha 2 chain [ Bos taurus (domestic cattle) ]

Gene ID: 515435, updated on 17-Aug-2024

Summary

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Official Symbol
COL11A2provided by VGNC
Official Full Name
collagen type XI alpha 2 chainprovided by VGNC
Primary source
VGNC:VGNC:27554
See related
Ensembl:ENSBTAG00000000601
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See COL11A2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
67
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7349362..7378844, complement)

Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene bromodomain containing 2 Neighboring gene major histocompatibility complex, class II, DO alpha Neighboring gene uncharacterized LOC132343598 Neighboring gene retinoid X receptor beta Neighboring gene solute carrier family 39 member 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative analysis of the bovine MHC class IIb sequence identifies inversion breakpoints and three unexpected genes. Childers CP, et al. Anim Genet, 2006 Apr. PMID 16573526
  2. The collagen family members as cell adhesion proteins. Heino J. Bioessays, 2007 Oct. PMID 17876790
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
collagen alpha-2(XI) chain
Names
collagen, type XI, alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046199.1 → NP_001039664.1  collagen alpha-2(XI) chain precursor

    See identical proteins and their annotated locations for NP_001039664.1

    Status: PROVISIONAL

    Source sequence(s)
    AY957499
    UniProtKB/Swiss-Prot
    Q32S24
    UniProtKB/TrEMBL
    F1MRP6
    Related
    ENSBTAP00000000793.5, ENSBTAT00000000793.7
    Conserved Domains (3) summary
    pfam01391
    Location:654 → 710
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1540 → 1735
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    7349362..7378844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024983579.2 → XP_024839347.1  collagen alpha-2(XI) chain isoform X1

    UniProtKB/TrEMBL
    F1MRP6
    Conserved Domains (4) summary
    pfam01391
    Location:712 → 768
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1598 → 1793
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains
    cl26386
    Location:296 → 662
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_005223247.5 → XP_005223304.1  collagen alpha-2(XI) chain isoform X8

    UniProtKB/TrEMBL
    A0AAA9U0X2, F1MRP6
    Related
    ENSBTAP00000102784.1, ENSBTAT00000104382.1
    Conserved Domains (3) summary
    pfam01391
    Location:547 → 603
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1433 → 1628
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

  3. XM_005223246.5 → XP_005223303.1  collagen alpha-2(XI) chain isoform X7

    UniProtKB/TrEMBL
    A0AAA9TJC4, F1MRP6
    Related
    ENSBTAP00000098425.1, ENSBTAT00000093929.1
    Conserved Domains (3) summary
    pfam01391
    Location:568 → 624
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1454 → 1649
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

  4. XM_010818042.4 → XP_010816344.1  collagen alpha-2(XI) chain isoform X4

    UniProtKB/TrEMBL
    A0AAA9RZS5, F1MRP6
    Related
    ENSBTAP00000075315.1, ENSBTAT00000122125.1
    Conserved Domains (3) summary
    pfam01391
    Location:628 → 684
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1514 → 1709
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

  5. XM_010818041.4 → XP_010816343.1  collagen alpha-2(XI) chain isoform X3

    UniProtKB/TrEMBL
    F1MRP6
    Conserved Domains (3) summary
    pfam01391
    Location:631 → 687
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1517 → 1712
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

  6. XM_024983580.2 → XP_024839348.1  collagen alpha-2(XI) chain isoform X2

    UniProtKB/TrEMBL
    F1MRP6
    Conserved Domains (4) summary
    pfam01391
    Location:652 → 708
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1538 → 1733
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains
    cl26386
    Location:236 → 602
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  7. XM_024983581.2 → XP_024839349.1  collagen alpha-2(XI) chain isoform X6

    UniProtKB/TrEMBL
    F1MRP6
    Conserved Domains (3) summary
    pfam01391
    Location:573 → 629
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:1459 → 1654
    COLFI; Fibrillar collagens C-terminal domain
    smart00210
    Location:31 → 213
    TSPN; Thrombospondin N-terminal -like domains

  8. XM_059880333.1 → XP_059736316.1  collagen alpha-2(XI) chain isoform X5

    UniProtKB/TrEMBL
    F1MRP6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q32S24.1 GenPept UniProtKB/Swiss-Prot:Q32S24

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