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APBB2 amyloid beta precursor protein binding family B member 2 [ Bos taurus (domestic cattle) ]

Gene ID: 514013, updated on 17-Aug-2024

Summary

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Official Symbol
APBB2provided by VGNC
Official Full Name
amyloid beta precursor protein binding family B member 2provided by VGNC
Primary source
VGNC:VGNC:26005
See related
BGD:BT11681; Ensembl:ENSBTAG00000027569
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (59711754..60095779, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 47 Neighboring gene uncharacterized LOC104968867 Neighboring gene NOP2/Sun RNA methyltransferase family member 7 Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene ubiquitin C-terminal hydrolase L1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC139640

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
amyloid beta precursor protein binding family B member 2
Names
amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like)
amyloid beta A4 precursor protein-binding, family B, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076847.1 → NP_001070315.1  amyloid beta precursor protein binding family B member 2

    See identical proteins and their annotated locations for NP_001070315.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123464
    UniProtKB/TrEMBL
    A0A3Q1MIA1, Q08E17
    Related
    ENSBTAP00000069418.2, ENSBTAT00000074557.2
    Conserved Domains (3) summary
    smart00456
    Location:290 → 321
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:582 → 708
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:415 → 554
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    59711754..60095779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059887472.1 → XP_059743455.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  2. XM_059887475.1 → XP_059743458.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6
    Related
    ENSBTAP00000039437.5, ENSBTAT00000039647.6

  3. XM_059887478.1 → XP_059743461.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  4. XM_024993182.2 → XP_024848950.1  amyloid beta precursor protein binding family B member 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MIA1
    Conserved Domains (3) summary
    smart00456
    Location:289 → 320
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:580 → 706
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:414 → 551
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  5. XM_059887480.1 → XP_059743463.1  amyloid beta precursor protein binding family B member 2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MIA1

  6. XM_024993181.2 → XP_024848949.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6
    Conserved Domains (3) summary
    smart00456
    Location:290 → 321
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:581 → 707
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:415 → 552
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  7. XM_059887481.1 → XP_059743464.1  amyloid beta precursor protein binding family B member 2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MIA1

  8. XM_059887476.1 → XP_059743459.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  9. XM_005207868.5 → XP_005207925.1  amyloid beta precursor protein binding family B member 2 isoform X6

    UniProtKB/TrEMBL
    A0A3Q1MIA1
    Conserved Domains (3) summary
    smart00456
    Location:289 → 320
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:558 → 684
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:393 → 530
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  10. XM_010806070.4 → XP_010804372.1  amyloid beta precursor protein binding family B member 2 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MIA1
    Conserved Domains (3) summary
    smart00456
    Location:289 → 320
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:559 → 685
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:393 → 530
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  11. XM_005207865.5 → XP_005207922.1  amyloid beta precursor protein binding family B member 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MIA1
    Conserved Domains (3) summary
    smart00456
    Location:289 → 320
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:580 → 706
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:414 → 551
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  12. XM_005207867.5 → XP_005207924.1  amyloid beta precursor protein binding family B member 2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MIA1
    Conserved Domains (3) summary
    smart00456
    Location:290 → 321
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:560 → 686
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:394 → 531
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  13. XM_059887479.1 → XP_059743462.1  amyloid beta precursor protein binding family B member 2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1MIA1

  14. XM_005207864.5 → XP_005207921.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6
    Conserved Domains (3) summary
    smart00456
    Location:290 → 321
    WW; Domain with 2 conserved Trp (W) residues
    cd01271
    Location:581 → 707
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:415 → 552
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

  15. XM_059887474.1 → XP_059743457.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  16. XM_059887473.1 → XP_059743456.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  17. XM_059887477.1 → XP_059743460.1  amyloid beta precursor protein binding family B member 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MIA1, F1MDE6

  18. XM_059887482.1 → XP_059743465.1  amyloid beta precursor protein binding family B member 2 isoform X8

  19. XM_024993184.2 → XP_024848952.1  amyloid beta precursor protein binding family B member 2 isoform X7

    Conserved Domains (1) summary
    cd01271
    Location:34 → 160
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain

  20. XM_059887483.1 → XP_059743466.1  amyloid beta precursor protein binding family B member 2 isoform X7

  21. XM_005207871.5 → XP_005207928.1  amyloid beta precursor protein binding family B member 2 isoform X7

    See identical proteins and their annotated locations for XP_005207928.1

    Conserved Domains (1) summary
    cd01271
    Location:34 → 160
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain

  22. XM_005207870.5 → XP_005207927.1  amyloid beta precursor protein binding family B member 2 isoform X10

    See identical proteins and their annotated locations for XP_005207927.1

    Conserved Domains (2) summary
    cd01271
    Location:89 → 215
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cl17171
    Location:14 → 60
    PH-like; Pleckstrin homology-like domain

  23. XM_005207869.5 → XP_005207926.1  amyloid beta precursor protein binding family B member 2 isoform X9

    See identical proteins and their annotated locations for XP_005207926.1

    Conserved Domains (2) summary
    cd01271
    Location:92 → 218
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cl17171
    Location:19 → 63
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein Strain
Heading Accession and Version

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