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PHF21A PHD finger protein 21A [ Homo sapiens (human) ]

Gene ID: 51317, updated on 10-Oct-2019

Summary

Official Symbol
PHF21Aprovided by HGNC
Official Full Name
PHD finger protein 21Aprovided by HGNC
Primary source
HGNC:HGNC:24156
See related
Ensembl:ENSG00000135365 MIM:608325
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BHC80; BM-006
Summary
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM, Nov 2010]
Expression
Ubiquitous expression in testis (RPKM 7.2), ovary (RPKM 5.9) and 25 other tissues See more
Orthologs

Genomic context

See PHF21A in Genome Data Viewer
Location:
11p11.2
Exon count:
28
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (45929319..46121203, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (45950870..46142985, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene LARGE xylosyl- and glucuronyltransferase 2 Neighboring gene Sharpr-MPRA regulatory region 8215 Neighboring gene uncharacterized LOC105376661 Neighboring gene filamin binding LIM protein 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated (2019-05-22)

ClinGen Genome Curation Page
Haploinsufficency

Some evidence for dosage pathogenicity (Last evaluated (2019-05-22)

ClinGen Genome Curation PagePubMed

NHGRI GWAS Catalog

Description
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
NHGRI GWA Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
NHGRI GWA Catalog
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
NHGRI GWA Catalog

Pathways from BioSystems

  • Chromatin modifying enzymes, organism-specific biosystem (from REACTOME)
    Chromatin modifying enzymes, organism-specific biosystemEukaryotic DNA is associated with histone proteins and organized into a complex nucleoprotein structure called chromatin. This structure decreases the accessibility of DNA but also helps to protect i...
  • Chromatin organization, organism-specific biosystem (from REACTOME)
    Chromatin organization, organism-specific biosystemChromatin organization refers to the composition and conformation of complexes between DNA, protein and RNA. It is determined by processes that result in the specification, formation or maintenance o...
  • Factors involved in megakaryocyte development and platelet production, organism-specific biosystem (from REACTOME)
    Factors involved in megakaryocyte development and platelet production, organism-specific biosystemMegakaryocytes (MKs) give rise to circulating platelets (thrombocytes) through terminal differentiation of MKs which release cytoplasmic fragments as circulating platelets. As MKs mature they underg...
  • HDACs deacetylate histones, organism-specific biosystem (from REACTOME)
    HDACs deacetylate histones, organism-specific biosystemLysine deacetylases (KDACs), historically referred to as histone deacetylases (HDACs), are divided into the Rpd3/Hda1 metal-dependent 'classical HDAC family' (de Ruijter et al. 2003, Verdin et al. 2...
  • Hemostasis, organism-specific biosystem (from REACTOME)
    Hemostasis, organism-specific biosystemHemostasis is a physiological response that culminates in the arrest of bleeding from an injured vessel. Under normal conditions the vascular endothelium supports vasodilation, inhibits platelet adhe...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1696

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
blood coagulation TAS
Traceable Author Statement
more info
 
chromatin organization IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
DNA repair complex IDA
Inferred from Direct Assay
more info
PubMed 
histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
PHD finger protein 21A
Names
BHC80a
BRAF35-HDAC complex protein BHC80
BRAF35/HDAC2 complex (80 kDa)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101802.2NP_001095272.1  PHD finger protein 21A isoform a

    See identical proteins and their annotated locations for NP_001095272.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AC068385, AL359608, BC015714
    Consensus CDS
    CCDS44578.1
    UniProtKB/Swiss-Prot
    Q96BD5
    Related
    ENSP00000398824.2, ENST00000418153.6
    Conserved Domains (3) summary
    cd15523
    Location:490532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:374536
    ING; Inhibitor of growth proteins N-terminal histone-binding
  2. NM_001352025.2NP_001338954.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c). Variants 3, 4, and 5 all encode isoform c.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  3. NM_001352026.2NP_001338955.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 3 and 5, encodes isoform c.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  4. NM_001352027.2NP_001338956.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 3 and 4, encodes isoform c.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  5. NM_001352028.1NP_001338957.1  PHD finger protein 21A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 2 and 7, encodes isoform b.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS31474.1
    Conserved Domains (2) summary
    cd15523
    Location:444486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  6. NM_001352029.1NP_001338958.1  PHD finger protein 21A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 2 and 6, encodes isoform b.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS31474.1
    Conserved Domains (2) summary
    cd15523
    Location:444486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  7. NM_001352030.2NP_001338959.1  PHD finger protein 21A isoform 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 9 and 10, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  8. NM_001352031.2NP_001338960.1  PHD finger protein 21A isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 8 and 10, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  9. NM_001352032.2NP_001338961.1  PHD finger protein 21A isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 8 and 9, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  10. NM_016621.4NP_057705.3  PHD finger protein 21A isoform b

    See identical proteins and their annotated locations for NP_057705.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, and includes an alternate in-frame exon in the 3' coding region, but lacks a different alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform b) is shorter than isoform a. Variants 2, 6, and 7 all encode the same isoform (b).
    Source sequence(s)
    AB051483, AC068385, AL359608
    Consensus CDS
    CCDS31474.1
    UniProtKB/Swiss-Prot
    Q96BD5
    Related
    ENSP00000323152.6, ENST00000323180.10
    Conserved Domains (2) summary
    cd15523
    Location:444486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain

RNA

  1. NR_147890.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC024475, AC068385

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    45929319..46121203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017901.1XP_016873390.1  PHD finger protein 21A isoform X13

  2. XM_011520158.2XP_011518460.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518460.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  3. XM_017017893.1XP_016873382.1  PHD finger protein 21A isoform X8

    Conserved Domains (2) summary
    COG5034
    Location:382544
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  4. XM_017017906.2XP_016873395.1  PHD finger protein 21A isoform X18

  5. XM_024448574.1XP_024304342.1  PHD finger protein 21A isoform X5

    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  6. XM_024448576.1XP_024304344.1  PHD finger protein 21A isoform X5

    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  7. XM_024448575.1XP_024304343.1  PHD finger protein 21A isoform X5

    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  8. XM_024448578.1XP_024304346.1  PHD finger protein 21A isoform X15

    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  9. XM_011520179.3XP_011518481.1  PHD finger protein 21A isoform X14

    See identical proteins and their annotated locations for XP_011518481.1

    UniProtKB/Swiss-Prot
    Q96BD5
    Conserved Domains (2) summary
    cd15523
    Location:444486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  10. XM_017017897.1XP_016873386.1  PHD finger protein 21A isoform X12

    Conserved Domains (2) summary
    COG5034
    Location:330492
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:446488
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  11. XM_017017905.1XP_016873394.1  PHD finger protein 21A isoform X17

    Conserved Domains (2) summary
    COG5034
    Location:298460
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:414456
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  12. XM_017017890.1XP_016873379.1  PHD finger protein 21A isoform X4

    Conserved Domains (2) summary
    cd15523
    Location:496538
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:380542
    ING; Inhibitor of growth proteins N-terminal histone-binding
  13. XM_017017889.1XP_016873378.1  PHD finger protein 21A isoform X3

    Conserved Domains (2) summary
    cd15523
    Location:497539
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:381543
    ING; Inhibitor of growth proteins N-terminal histone-binding
  14. XM_017017896.1XP_016873385.1  PHD finger protein 21A isoform X11

  15. XM_017017888.1XP_016873377.1  PHD finger protein 21A isoform X2

    Conserved Domains (2) summary
    cd15523
    Location:497539
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:381543
    ING; Inhibitor of growth proteins N-terminal histone-binding
  16. XM_017017895.1XP_016873384.1  PHD finger protein 21A isoform X10

  17. XM_017017894.1XP_016873383.1  PHD finger protein 21A isoform X9

    Conserved Domains (1) summary
    cd15523
    Location:451493
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  18. XM_017017908.1XP_016873397.1  PHD finger protein 21A isoform X20

  19. XM_017017886.1XP_016873375.1  PHD finger protein 21A isoform X1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  20. XM_017017900.1XP_016873389.1  PHD finger protein 21A isoform X12

    Conserved Domains (2) summary
    COG5034
    Location:330492
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:446488
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  21. XM_011520164.2XP_011518466.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518466.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  22. XM_011520167.2XP_011518469.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518469.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  23. XM_011520161.2XP_011518463.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518463.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  24. XM_017017907.1XP_016873396.1  PHD finger protein 21A isoform X19

    Conserved Domains (3) summary
    COG5034
    Location:291453
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:407449
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  25. XM_017017892.1XP_016873381.1  PHD finger protein 21A isoform X7

    Conserved Domains (3) summary
    cd15523
    Location:490532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:374536
    ING; Inhibitor of growth proteins N-terminal histone-binding
  26. XM_017017902.1XP_016873391.1  PHD finger protein 21A isoform X16

    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  27. XM_017017891.1XP_016873380.1  PHD finger protein 21A isoform X6

    UniProtKB/Swiss-Prot
    Q96BD5
    Conserved Domains (3) summary
    cd15523
    Location:490532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:374536
    ING; Inhibitor of growth proteins N-terminal histone-binding
  28. XM_024448577.1XP_024304345.1  PHD finger protein 21A isoform X15

    Conserved Domains (2) summary
    cd15523
    Location:443485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
  29. XM_011520157.2XP_011518459.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518459.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  30. XM_017017887.2XP_016873376.1  PHD finger protein 21A isoform X1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  31. XM_011520166.3XP_011518468.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518468.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  32. XM_017017885.2XP_016873374.1  PHD finger protein 21A isoform X1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  33. XM_011520162.3XP_011518464.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518464.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  34. XM_011520160.3XP_011518462.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518462.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  35. XM_005252965.4XP_005253022.1  PHD finger protein 21A isoform X5

    See identical proteins and their annotated locations for XP_005253022.1

    UniProtKB/Swiss-Prot
    Q96BD5
    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  36. XM_017017899.1XP_016873388.1  PHD finger protein 21A isoform X12

    Conserved Domains (2) summary
    COG5034
    Location:330492
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:446488
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
  37. XM_011520168.2XP_011518470.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518470.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  38. XM_011520175.2XP_011518477.1  PHD finger protein 21A isoform X7

    See identical proteins and their annotated locations for XP_011518477.1

    Conserved Domains (3) summary
    cd15523
    Location:490532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:374536
    ING; Inhibitor of growth proteins N-terminal histone-binding
  39. XM_011520174.2XP_011518476.1  PHD finger protein 21A isoform X5

    See identical proteins and their annotated locations for XP_011518476.1

    UniProtKB/Swiss-Prot
    Q96BD5
    Conserved Domains (3) summary
    cd15523
    Location:491533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:362
    STAT_alpha; STAT protein, all-alpha domain
    cl26267
    Location:375537
    ING; Inhibitor of growth proteins N-terminal histone-binding
  40. XM_011520165.2XP_011518467.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518467.1

    Conserved Domains (2) summary
    cd15523
    Location:498540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382544
    ING; Inhibitor of growth proteins N-terminal histone-binding
  41. XM_017017898.2XP_016873387.1  PHD finger protein 21A isoform X12

    Conserved Domains (2) summary
    COG5034
    Location:330492
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:446488
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

RNA

  1. XR_001747900.1 RNA Sequence

  2. XR_001747902.2 RNA Sequence

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