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GASK1B golgi associated kinase 1B [ Homo sapiens (human) ]

Gene ID: 51313, updated on 26-Sep-2020

Summary

Official Symbol
GASK1Bprovided by HGNC
Official Full Name
golgi associated kinase 1Bprovided by HGNC
Primary source
HGNC:HGNC:25312
See related
Ensembl:ENSG00000164125
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ENED; AD021; AD036; C4orf18; FAM198B
Expression
Broad expression in adrenal (RPKM 128.3), ovary (RPKM 68.9) and 17 other tissues See more
Orthologs

Genomic context

See GASK1B in Genome Data Viewer
Location:
4q32.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (158124474..158173075, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (159045732..159094202, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377509 Neighboring gene GATA motif-containing MPRA enhancer 19 Neighboring gene ribosomal protein L6 pseudogene Neighboring gene FAM198B antisense RNA 1 Neighboring gene uncharacterized LOC101928007 Neighboring gene NUDT19 pseudogene 5 Neighboring gene transmembrane protein 144

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23966, FLJ38155, DKFZp434L142

Gene Ontology Provided by GOA

Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Golgi-associated kinase 1B
Names
expressed in nerve and epithelium during development
family with sequence similarity 198 member B
protein FAM198B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031700.3NP_001026870.2  Golgi-associated kinase 1B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC098679, BC017701, BC043193, DA887770
    Consensus CDS
    CCDS34087.1
    UniProtKB/Swiss-Prot
    Q6UWH4
    UniProtKB/TrEMBL
    Q9NYZ0
    Related
    ENSP00000377396.4, ENST00000393807.9
    Conserved Domains (1) summary
    pfam15051
    Location:203526
    FAM198; FAM198 protein
  2. NM_001128424.2NP_001121896.1  Golgi-associated kinase 1B isoform 2

    See identical proteins and their annotated locations for NP_001121896.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Variants 2 and 3 both encode isoform 2.
    Source sequence(s)
    AC098679, AY358785, BC017701, BC043193, DA887770
    Consensus CDS
    CCDS3798.1
    UniProtKB/Swiss-Prot
    Q6UWH4
    UniProtKB/TrEMBL
    Q9NYZ0
    Related
    ENSP00000465976.1, ENST00000585682.5
    Conserved Domains (1) summary
    pfam15051
    Location:203518
    FAM198; FAM198 protein
  3. NM_016613.7NP_057697.2  Golgi-associated kinase 1B isoform 2

    See identical proteins and their annotated locations for NP_057697.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Variants 2 and 3 both encode isoform 2.
    Source sequence(s)
    AC098679, AY358785, BC017701, BX489659, DA887770
    Consensus CDS
    CCDS3798.1
    UniProtKB/Swiss-Prot
    Q6UWH4
    UniProtKB/TrEMBL
    Q9NYZ0
    Related
    ENSP00000296530.7, ENST00000296530.12
    Conserved Domains (1) summary
    pfam15051
    Location:203518
    FAM198; FAM198 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    158124474..158173075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024454079.1XP_024309847.1  Golgi-associated kinase 1B isoform X1

    Conserved Domains (1) summary
    pfam15051
    Location:203518
    FAM198; FAM198 protein
  2. XM_024454078.1XP_024309846.1  Golgi-associated kinase 1B isoform X1

    Conserved Domains (1) summary
    pfam15051
    Location:203518
    FAM198; FAM198 protein
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