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TFDP3 transcription factor Dp family member 3 [ Homo sapiens (human) ]

Gene ID: 51270, updated on 10-Dec-2019

Summary

Official Symbol
TFDP3provided by HGNC
Official Full Name
transcription factor Dp family member 3provided by HGNC
Primary source
HGNC:HGNC:24603
See related
Ensembl:ENSG00000183434 MIM:300772
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DP4; CT30; HCA661
Summary
This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.[provided by RefSeq, May 2010]
Orthologs

Genomic context

See TFDP3 in Genome Data Viewer
Location:
Xq26.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (133216662..133218354, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (132350697..132352376, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107983959 Neighboring gene DEAD-box helicase 53 pseudogene Neighboring gene RNA, U1 small nuclear 115, pseudogene Neighboring gene glypican 4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC161639

Gene Ontology Provided by GOA

Process Evidence Code Pubs
G1/S transition of mitotic cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to DNA damage stimulus IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcription factor Dp family member 3
Names
E2F-like protein
cancer/testis antigen 30
hepatocellular carcinoma-associated antigen 661

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021355.1 RefSeqGene

    Range
    4995..6687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_016521.3NP_057605.3  transcription factor Dp family member 3

    See identical proteins and their annotated locations for NP_057605.3

    Status: REVIEWED

    Source sequence(s)
    AF219119, Z77249
    Consensus CDS
    CCDS14636.2
    UniProtKB/Swiss-Prot
    Q5H9I0
    Related
    ENSP00000385461.1, ENST00000310125.5
    Conserved Domains (3) summary
    cd14458
    Location:193239
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:108188
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:195334
    DP; Transcription factor DP

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    133216662..133218354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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