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CDKN2A-DT CDKN2A divergent transcript [ Homo sapiens (human) ]

Gene ID: 51198, updated on 4-May-2023

Summary

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Official Symbol
CDKN2A-DTprovided by HGNC
Official Full Name
CDKN2A divergent transcriptprovided by HGNC
Primary source
HGNC:HGNC:23831
See related
AllianceGenome:HGNC:23831
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C9orf53; bA149I2.3; CDKN2A-AS1
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Genomic context

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See CDKN2A-DT in Genome Data Viewer
Location:
9p21.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (21967139..21967754)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (21981439..21982054)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (21967138..21967753)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 9:21959860 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 9:21962977 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:21968891-21969804 Neighboring gene cyclin dependent kinase inhibitor 2A Neighboring gene uncharacterized LOC124902130 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:21989455-21990037

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry. Scheffold T, et al. BMC Cardiovasc Disord, 2011 Mar 7. PMID 21385355, Free PMC Article
  2. Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease. Emanuele E, et al. Neurobiol Aging, 2011 Jul. PMID 19664850
  3. The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study. Shiffman D, et al. BMC Cardiovasc Disord, 2011 Mar 15. PMID 21406102, Free PMC Article
  4. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. Casabonne D, et al. Haematologica, 2011 Feb. PMID 21048031, Free PMC Article
  5. DNA sequence and analysis of human chromosome 9. Humphray SJ, et al. Nature, 2004 May 27. PMID 15164053, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The C allele of rs1333049 in the vascular disease susceptibility locus is associated with vascular dementia and late-onset Alzheimer's disease, independent of traditional risk factors.
    Title: Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease.
  2. Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction.
    Title: Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry.
  3. A chromosome 9p21.3 variant predicts the risk of myocardial infarction among white men.
    Title: The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study.
  4. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • CDKN2A antisense RNA 1 (head to head)
  • susceptibility protein NSG-x

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024274.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF211119, BX091351

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    21967139..21967754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    21981439..21982054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_016349.1: Suppressed sequence

    Description
    NM_016349.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9UH64.1 GenPept UniProtKB/Swiss-Prot:Q9UH64

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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