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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001134778.2 → NP_001128250.1 pre-B-cell leukemia transcription factor 3 isoform 2
See identical proteins and their annotated locations for NP_001128250.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) utilizes an alternate first exon and 5'UTR; thus, the first likely translation initiation site corresponds to an internal methionine in variant 1. The predicted protein (isoform 2) is N-terminally truncated compared to isoform 1 and is not predicted to have a signal peptide.
- Source sequence(s)
-
AK309713, AL358074, BC094883, CD675622, CN372830, CN372832
- Consensus CDS
-
CCDS48021.1
- UniProtKB/Swiss-Prot
-
P40426
- Related
- ENSP00000387456.2, ENST00000447726.6
- Conserved Domains (2) summary
-
- cd00086
Location:161 → 221
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- pfam03792
Location:1 → 159
- PBC; PBC domain
-
NM_001330782.2 → NP_001317711.1 pre-B-cell leukemia transcription factor 3 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AL358074, AL445186, BC094883, BP340711, DA692140
- Consensus CDS
-
CCDS83416.1
- UniProtKB/Swiss-Prot
-
P40426
- Related
- ENSP00000341990.5, ENST00000342287.9
- Conserved Domains (2) summary
-
- cd00086
Location:236 → 296
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- pfam03792
Location:43 → 234
- PBC; PBC domain
-
NM_001411009.1 → NP_001397938.1 pre-B-cell leukemia transcription factor 3 isoform 4
Status: VALIDATED
- Source sequence(s)
-
AL358074, AL445186
- Consensus CDS
-
CCDS94482.1
- UniProtKB/TrEMBL
-
Q5JS98
-
NM_006195.6 → NP_006186.1 pre-B-cell leukemia transcription factor 3 isoform 1
See identical proteins and their annotated locations for NP_006186.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) utilizes an alternate first exon containing a predicted translation initiation site with a strong Kozak signal; the resulting protein isoform (1) is predicted to have a signal peptide.
- Source sequence(s)
-
BC016977, BC094883, X59841
- Consensus CDS
-
CCDS6865.1
- UniProtKB/Swiss-Prot
- P40426, Q96PG0
- UniProtKB/TrEMBL
-
Q96AL5
- Related
- ENSP00000362588.5, ENST00000373489.10
- Conserved Domains (2) summary
-
- cd00086
Location:236 → 296
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- pfam03792
Location:43 → 234
- PBC; PBC domain
RNA
-
NR_024122.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) omits a coding exon resulting in a frameshift and truncated open reading frame. The transcript is predicted to be a candidate for nonsense-mediated decay and likely does not encode a protein.
- Source sequence(s)
-
AF355141, AI479638, BC094883, CD675622, CN372830, CN372832, X59841
-
NR_024123.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) omits two coding exons resulting in a frameshift and truncated open reading frame. The transcript is predicted to be a candidate for nonsense-mediated decay and likely does not encode a protein.
- Source sequence(s)
-
AF355142, AI479638, BC094883, CD675622, CN372830, CN372832, X59841
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000009.12 Reference GRCh38.p14 Primary Assembly
- Range
-
125747373..125967377
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006717130.2 → XP_006717193.1 pre-B-cell leukemia transcription factor 3 isoform X1
- UniProtKB/TrEMBL
-
Q5JS98
- Related
- ENSP00000362586.4, ENST00000373487.8
- Conserved Domains (2) summary
-
- cd00086
Location:236 → 317
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- pfam03792
Location:43 → 234
- PBC; PBC domain
-
XM_047423441.1 → XP_047279397.1 pre-B-cell leukemia transcription factor 3 isoform X3
-
XM_047423443.1 → XP_047279399.1 pre-B-cell leukemia transcription factor 3 isoform X5
-
XM_011518755.3 → XP_011517057.1 pre-B-cell leukemia transcription factor 3 isoform X2
- Conserved Domains (2) summary
-
- cd00086
Location:161 → 242
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- pfam03792
Location:1 → 159
- PBC; PBC domain
-
XM_047423445.1 → XP_047279401.1 pre-B-cell leukemia transcription factor 3 isoform X7
-
XM_047423442.1 → XP_047279398.1 pre-B-cell leukemia transcription factor 3 isoform X4
-
XM_047423444.1 → XP_047279400.1 pre-B-cell leukemia transcription factor 3 isoform X6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060933.1 Alternate T2T-CHM13v2.0
- Range
-
137947324..138172756
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)