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TAS2R9 taste 2 receptor member 9 [ Homo sapiens (human) ]

Gene ID: 50835, updated on 25-Jan-2022

Summary

Official Symbol
TAS2R9provided by HGNC
Official Full Name
taste 2 receptor member 9provided by HGNC
Primary source
HGNC:HGNC:14917
See related
Ensembl:ENSG00000121381 MIM:604795; AllianceGenome:HGNC:14917
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R9; TRB6
Summary
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See TAS2R9 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (10809094..10810168, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (10961693..10962767, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene taste 2 receptor member 7 Neighboring gene taste 2 receptor member 8 Neighboring gene uncharacterized LOC107984459 Neighboring gene taste 2 receptor member 10 Neighboring gene taste 2 receptor member 7 pseudogene

Genomic regions, transcripts, and products

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables taste receptor activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 9
Names
taste receptor, family B, member 6
taste receptor, type 2, member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023917.2NP_076406.1  taste receptor type 2 member 9

    See identical proteins and their annotated locations for NP_076406.1

    Status: REVIEWED

    Source sequence(s)
    BC069066, BC095519
    Consensus CDS
    CCDS8633.1
    UniProtKB/Swiss-Prot
    Q9NYW1
    Related
    ENSP00000240691.2, ENST00000240691.4
    Conserved Domains (1) summary
    pfam05296
    Location:1301
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    10809094..10810168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    7800..8874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_187658.1 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    7800..8874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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