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TAS2R4 taste 2 receptor member 4 [ Homo sapiens (human) ]

Gene ID: 50832, updated on 22-Mar-2020

Summary

Official Symbol
TAS2R4provided by HGNC
Official Full Name
taste 2 receptor member 4provided by HGNC
Primary source
HGNC:HGNC:14911
See related
Ensembl:ENSG00000127364 MIM:604869
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R4
Summary
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See TAS2R4 in Genome Data Viewer
Location:
7q34
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (141776674..141781691)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (141478289..141479188)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene single stranded DNA binding protein 1 Neighboring gene taste 2 receptor member 3 Neighboring gene taste 2 receptor member 6 pseudogene Neighboring gene taste 2 receptor member 5

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • MGC163311

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
taste receptor activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
ciliary membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IC
Inferred by Curator
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 4
Names
candidate taste receptor T2R4
taste receptor, type 2, member 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016944.2NP_058640.1  taste receptor type 2 member 4

    See identical proteins and their annotated locations for NP_058640.1

    Status: REVIEWED

    Source sequence(s)
    AC004979
    Consensus CDS
    CCDS5868.1
    UniProtKB/Swiss-Prot
    Q9NYW5
    Related
    ENSP00000247881.2, ENST00000247881.3
    Conserved Domains (1) summary
    pfam05296
    Location:1299
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    141776674..141781691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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