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Rbis ribosomal biogenesis factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 499567, updated on 5-Mar-2024

Summary

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Official Symbol
Rbisprovided by RGD
Official Full Name
ribosomal biogenesis factorprovided by RGD
Primary source
RGD:1565641
See related
Ensembl:ENSRNOG00000064945 AllianceGenome:RGD:1565641
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565641
Summary
Predicted to be involved in ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human RBIS (ribosomal biogenesis factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 249.7), Kidney (RPKM 205.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
2q23
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (88702599..88718587)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (86981314..86997352)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (88338018..88350785)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene carbonic anhydrase 1 Neighboring gene carbonic anhydrase 13 Neighboring gene peroxiredoxin like 2A, pseudogene 1 Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene E2F transcription factor 5 Neighboring gene leucine rich repeat and coiled-coil centrosomal protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells. Badertscher L, et al. Cell Rep, 2015 Dec 29. PMID 26711351
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ribosomal biogenesis factor
Names
uncharacterized protein C8orf59 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109179.1 → NP_001102649.1  ribosomal biogenesis factor

    See identical proteins and their annotated locations for NP_001102649.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473961
    UniProtKB/TrEMBL
    A6IH16
    Conserved Domains (1) summary
    pfam15679
    Location:1 → 97
    DUF4665; Domain of unknown function (DUF4665)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    88702599..88718587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006232114.5 → XP_006232176.1  ribosomal biogenesis factor isoform X3

    See identical proteins and their annotated locations for XP_006232176.1

    UniProtKB/TrEMBL
    A6IH16
    Conserved Domains (1) summary
    pfam15679
    Location:1 → 97
    DUF4665; Domain of unknown function (DUF4665)

  2. XM_039102857.2 → XP_038958785.1  ribosomal biogenesis factor isoform X3

    UniProtKB/TrEMBL
    A6IH16
    Conserved Domains (1) summary
    pfam15679
    Location:1 → 97
    DUF4665; Domain of unknown function (DUF4665)

  3. XM_039102855.2 → XP_038958783.1  ribosomal biogenesis factor isoform X2

    UniProtKB/TrEMBL
    D3ZXR6
    Related
    ENSRNOP00000056222.3
    Conserved Domains (1) summary
    pfam15679
    Location:56 → 152
    DUF4665; Domain of unknown function (DUF4665)

  4. XM_039102854.2 → XP_038958782.1  ribosomal biogenesis factor isoform X1

    Conserved Domains (1) summary
    pfam15679
    Location:64 → 160
    DUF4665; Domain of unknown function (DUF4665)
Nucleotide Protein Strain
Heading Accession and Version

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