Format

Send to:

Choose Destination

OR3A1 olfactory receptor family 3 subfamily A member 1 [ Homo sapiens (human) ]

Gene ID: 4994, updated on 5-Jan-2022

Summary

Official Symbol
OR3A1provided by HGNC
Official Full Name
olfactory receptor family 3 subfamily A member 1provided by HGNC
Primary source
HGNC:HGNC:8282
See related
Ensembl:ENSG00000180090
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR40; OLFRA03; OR17-40; OR17-82
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR3A1 in Genome Data Viewer
Location:
17p13.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (3288318..3299190, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (3194311..3201654, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 1 subfamily D member 4 Neighboring gene olfactory receptor family 1 subfamily D member 3 pseudogene Neighboring gene olfactory receptor family 3 subfamily A member 2 Neighboring gene olfactory receptor family 3 subfamily A member 4 pseudogene Neighboring gene olfactory receptor family 3 subfamily A member 5 pseudogene Neighboring gene olfactory receptor family 1 subfamily AC member 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 3A1
Names
Olfactory receptor-like protein OR17-82
olfactory receptor 17-40
olfactory receptor OR17-15

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002550.3NP_002541.2  olfactory receptor 3A1

    See identical proteins and their annotated locations for NP_002541.2

    Status: VALIDATED

    Source sequence(s)
    AC087498
    Consensus CDS
    CCDS11023.1
    UniProtKB/Swiss-Prot
    P47881
    UniProtKB/TrEMBL
    A0A126GVP1
    Related
    ENSP00000313803.1, ENST00000323404.2
    Conserved Domains (2) summary
    cd14964
    Location:3054
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:28304
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    3288318..3299190 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024695.1XP_016880184.1  olfactory receptor 3A1 isoform X1

    UniProtKB/Swiss-Prot
    P47881
    UniProtKB/TrEMBL
    A0A126GVP1
    Conserved Domains (2) summary
    cd14964
    Location:3054
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:28304
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Support Center