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SPANXN1 SPANX family member N1 [ Homo sapiens (human) ]

Gene ID: 494118, updated on 13-May-2022

Summary

Official Symbol
SPANXN1provided by HGNC
Official Full Name
SPANX family member N1provided by HGNC
Primary source
HGNC:HGNC:33174
See related
Ensembl:ENSG00000203923 MIM:300664; AllianceGenome:HGNC:33174
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT11.6
Summary
This gene represents one of several duplicated family members that are located on chromosome X. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members. [provided by RefSeq, May 2010]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See SPANXN1 in Genome Data Viewer
Location:
Xq27.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (145247503..145256208)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (143506427..143515132)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (144329023..144337728)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 189 Neighboring gene CYCS pseudogene 44 Neighboring gene TRMT1 pseudogene 1 Neighboring gene UFM1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
sperm protein associated with the nucleus on the X chromosome N1
Names
cancer/testis antigen family 11, member 6
nuclear-associated protein SPAN-Xn1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021225.1 RefSeqGene

    Range
    4917..13622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001009614.3NP_001009614.1  sperm protein associated with the nucleus on the X chromosome N1

    See identical proteins and their annotated locations for NP_001009614.1

    Status: REVIEWED

    Source sequence(s)
    AL356499, AL713923, DQ336118
    Consensus CDS
    CCDS35421.1
    UniProtKB/Swiss-Prot
    Q5VSR9
    Related
    ENSP00000359524.3, ENST00000370493.4
    Conserved Domains (1) summary
    pfam07458
    Location:172
    SPAN-X; Sperm protein associated with nucleus, mapped to X chromosome

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    145247503..145256208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    143506427..143515132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)