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LIAS lipoic acid synthetase [ Pan troglodytes (chimpanzee) ]

Gene ID: 471170, updated on 17-Aug-2024

Summary

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Official Symbol
LIASprovided by VGNC
Official Full Name
lipoic acid synthetaseprovided by VGNC
Primary source
VGNC:VGNC:750
Locus tag
CK820_G0003751
See related
Ensembl:ENSPTRG00000015994
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 3 NC_072401.2 (39787419..39806061)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (39787439..39806035)

Chromosome 3 - NC_072401.2Genomic Context describing neighboring genes Neighboring gene klotho beta Neighboring gene ribosomal protein L9 Neighboring gene WD repeat-containing protein 5-like Neighboring gene UDP-glucose 6-dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipoate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipoate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lipoyl synthase, mitochondrial
XP_001141481.1
XP_054539735.1
XP_526552.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    39787419..39806061
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_526552.5 → XP_526552.2  lipoyl synthase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_526552.2

    UniProtKB/TrEMBL
    A0A2I3TIW1, A0A2J8PGV6, A0A2J8PGW2, A0A6D2X699, A0A6D2Y506, H2QPC8
    Related
    ENSPTRP00000027528.1
    Conserved Domains (1) summary
    PLN02428
    Location:22 → 370
    PLN02428; lipoic acid synthase

  2. XM_001141481.4 → XP_001141481.1  lipoyl synthase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2I3T031, A0A2I3T2Y0, A0A2J8PGU6, A0A2J8PGW1, A0A6D2VTX3, A0A6D2Y262
    Related
    ENSPTRP00000082606.1
    Conserved Domains (1) summary
    cl26932
    Location:22 → 319
    LipA; Lipoate synthase [Coenzyme transport and metabolism]

  3. XM_054683760.1 → XP_054539735.1  lipoyl synthase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2I3SAH0, A0A2I3SRE5, A0A2J8PGV5, A0A2J8PGX1, A0A6D2XSZ3, A0A6D2Y4S1
Nucleotide Protein
Heading Accession and Version

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