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NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 [ Homo sapiens (human) ]

Gene ID: 4696, updated on 10-Dec-2024

Summary

Official Symbol
NDUFA3provided by HGNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit A3provided by HGNC
Primary source
HGNC:HGNC:7686
See related
Ensembl:ENSG00000170906 MIM:603832; AllianceGenome:HGNC:7686
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
B9; CI-B9
Summary
Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial inner membrane and respiratory chain complex I. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in kidney (RPKM 30.6), fat (RPKM 26.2) and 25 other tissues See more
Orthologs
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Genomic context

See NDUFA3 in Genome Data Viewer
Location:
19q13.42
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (54102855..54107568)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (57180922..57186265)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (54606163..54610875)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene T cell-interacting, activating receptor on myeloid cells 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:54605952-54606928 Neighboring gene osteoclast associated Ig-like receptor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:54617323-54618196 Neighboring gene TCF3 fusion partner Neighboring gene PRPF31 antisense RNA 1 Neighboring gene pre-mRNA processing factor 31 Neighboring gene CCR4-NOT transcription complex subunit 3 Neighboring gene uncharacterized LOC102724273

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Names
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NADH-ubiquinone oxidoreductase B9 subunit
complex I B9 subunit
complex I-B9
NP_004533.1
XP_054177044.1
XP_054185658.1
XP_054186153.1
XP_054186450.1
XP_054186933.1
XP_054187214.1
XP_054187489.1
XP_054189529.1
XP_054189630.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004542.4NP_004533.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

    See identical proteins and their annotated locations for NP_004533.1

    Status: VALIDATED

    Source sequence(s)
    AC245052, BC061644
    Consensus CDS
    CCDS12877.1
    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4
    Related
    ENSP00000418438.1, ENST00000485876.6
    Conserved Domains (1) summary
    pfam14987
    Location:784
    NADHdh_A3; NADH dehydrogenase 1 alpha subcomplex subunit 3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    54102855..54107568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571054.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054329683.1XP_054185658.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NW_003571055.2 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    76759..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330178.1XP_054186153.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NW_003571056.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330475.1XP_054186450.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

  1. NW_003571057.2 Reference GRCh38.p14 ALT_REF_LOCI_4

    Range
    77276..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NW_003571058.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330958.1XP_054186933.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NW_003571059.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331239.1XP_054187214.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

  1. NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331514.1XP_054187489.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_8

Genomic

  1. NW_003571061.2 Reference GRCh38.p14 ALT_REF_LOCI_8

    Range
    76759..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333554.1XP_054189529.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

  1. NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

    Range
    76646..81988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333655.1XP_054189630.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    57180922..57186265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054321069.1XP_054177044.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X1

    UniProtKB/Swiss-Prot
    O95167
    UniProtKB/TrEMBL
    Q6FGG4