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PRLR prolactin receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 461925, updated on 10-Oct-2024

Summary

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Official Symbol
PRLRprovided by VGNC
Official Full Name
prolactin receptorprovided by VGNC
Primary source
VGNC:VGNC:13568
Locus tag
CK820_G0044897
See related
Ensembl:ENSPTRG00000016787
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PRLR in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (77560385..77741328)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (77748146..77922203)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene parathymosin-like Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC134810085 Neighboring gene alanine--glyoxylate aminotransferase 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables prolactin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prolactin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    77560385..77741328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001150064.8 → XP_001150064.2  prolactin receptor isoform X1

    See identical proteins and their annotated locations for XP_001150064.2

    UniProtKB/TrEMBL
    A0A2J8JSG6, A0A6D2XPN4, H2QQR5
    Related
    ENSPTRP00000028787.4
    Conserved Domains (3) summary
    cd00063
    Location:127 → 225
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:286 → 362
    GHBP; Growth hormone receptor binding
    cl21522
    Location:24 → 120
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_063811324.1 → XP_063667394.1  prolactin receptor isoform X2

    UniProtKB/TrEMBL
    A0A2I3RRC9, A0A2J8JSH6, A0A6D2XNE8

  3. XM_063811323.1 → XP_063667393.1  prolactin receptor isoform X1

    UniProtKB/TrEMBL
    A0A2J8JSG6, A0A6D2XPN4, H2QQR5

  4. XM_016953442.4 → XP_016808931.1  prolactin receptor isoform X1

    UniProtKB/TrEMBL
    A0A2J8JSG6, A0A6D2XPN4, H2QQR5
    Conserved Domains (3) summary
    cd00063
    Location:127 → 225
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12772
    Location:286 → 362
    GHBP; Growth hormone receptor binding
    cl21522
    Location:24 → 120
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RNA

  1. XR_001717767.4 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials