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PDE5A phosphodiesterase 5A [ Pan troglodytes (chimpanzee) ]

Gene ID: 461461, updated on 17-Aug-2024

Summary

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Official Symbol
PDE5Aprovided by VGNC
Official Full Name
phosphodiesterase 5Aprovided by VGNC
Primary source
VGNC:VGNC:2966
Locus tag
CK820_G0025836
See related
Ensembl:ENSPTRG00000016400
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 3 NC_072401.2 (120657774..120791900, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (120657748..120791970, complement)

Chromosome 3 - NC_072401.2Genomic Context describing neighboring genes Neighboring gene kelch-like protein 2 Neighboring gene uncharacterized LOC134806989 Neighboring gene uncharacterized LOC129143847 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134809806 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene uncharacterized LOC104006187 Neighboring gene uncharacterized LOC107974390

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-specific 3',5'-cyclic phosphodiesterase
Names
phosphodiesterase 5A, cGMP-specific
XP_001150967.3
XP_009446478.1
XP_009446480.1
XP_016807612.1
XP_016807613.1
XP_063665066.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    120657774..120791900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009448203.5 → XP_009446478.1  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X5

    See identical proteins and their annotated locations for XP_009446478.1

    UniProtKB/TrEMBL
    A0A2I3TS75, A0A2J8LWW2, A0A6D2WIM6, H2R206
    Related
    ENSPTRP00000043194.3
    Conserved Domains (2) summary
    smart00065
    Location:164 → 321
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:612 → 843
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_016952124.4 → XP_016807613.1  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3

    UniProtKB/TrEMBL
    A0A2I3TS75
    Conserved Domains (2) summary
    smart00065
    Location:164 → 321
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:563 → 798
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  3. XM_063808996.1 → XP_063665066.1  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X4

    UniProtKB/TrEMBL
    A0A2I3TS75, A0A2J8LX12

  4. XM_009448205.5 → XP_009446480.1  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X4

    See identical proteins and their annotated locations for XP_009446480.1

    UniProtKB/TrEMBL
    A0A2I3TS75, A0A2J8LX12
    Related
    ENSPTRP00000092555.1
    Conserved Domains (2) summary
    smart00065
    Location:112 → 269
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:560 → 791
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  5. XM_001150967.7 → XP_001150967.3  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2

    UniProtKB/TrEMBL
    A0A2I3TS75, A0A2J8LX42, A0A6D2Y0V6, K7B2Y0
    Related
    ENSPTRP00000067260.1
    Conserved Domains (2) summary
    smart00065
    Location:122 → 279
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:570 → 801
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  6. XM_016952123.4 → XP_016807612.1  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A2I3TS75
Nucleotide Protein
Heading Accession and Version

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