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STAT5A signal transducer and activator of transcription 5A [ Pan troglodytes (chimpanzee) ]

Gene ID: 454681, updated on 10-Oct-2024

Summary

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Official Symbol
STAT5Aprovided by VGNC
Official Full Name
signal transducer and activator of transcription 5Aprovided by VGNC
Primary source
VGNC:VGNC:9664
Locus tag
CK820_G0038991
See related
Ensembl:ENSPTRG00000009199
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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Genomic context

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See STAT5A in Genome Data Viewer
Location:
chromosome: 19
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (25833040..25856376, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (24017501..24041111, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene signal transducer and activator of transcription 5B Neighboring gene GH3 domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    25833040..25856376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024350293.3 → XP_024206061.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A2J8KFX0, A0A8I3B2M0, K7AB55, K7BSV1, K7D090
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_024350295.3 → XP_024206063.1  signal transducer and activator of transcription 5A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KFY2
    Conserved Domains (4) summary
    pfam01017
    Location:141 → 330
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:332 → 582
    STAT_bind; STAT protein, DNA binding domain
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 688
    SH2; Src homology 2 (SH2) domain

  3. XM_063798572.1 → XP_063654642.1  signal transducer and activator of transcription 5A isoform X4

  4. XM_024350294.3 → XP_024206062.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KFV5, K7BSV1
    Conserved Domains (4) summary
    cd10421
    Location:543 → 682
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:109 → 300
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:302 → 459
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 95
    STAT_int; STAT protein, protein interaction domain
Nucleotide Protein
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