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pknI serine/threonine protein kinase PknI [ Mycobacterium canettii CIPT 140010059 ]

Gene ID: 45426901, updated on 1-Aug-2024

Summary

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Gene symbol
pknI
Gene description
serine/threonine protein kinase PknI
Locus tag
MCAN_RS15430
Gene type
protein coding
Organism
Mycobacterium canettii CIPT 140010059 (strain: CIPT 140010059)
Lineage
Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Old locus tag
MCAN_29351
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Genomic context

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Sequence:
NC_015848.1 (3280675..3282432, complement)

NC_015848.1Genomic Context describing neighboring genes Neighboring gene TetR/AcrR family transcriptional regulator Neighboring gene amidohydrolase family protein Neighboring gene amidohydrolase family protein Neighboring gene signal recognition particle protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_015848.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation. Lisa MN, et al. FEBS J, 2017 Feb. PMID 28054744
  2. Homology modelling, docking, pharmacophore and site directed mutagenesis analysis to identify the critical amino acid residue of PknI from Mycobacterium tuberculosis. Kandasamy S, et al. J Mol Graph Model, 2014 Jul. PMID 24955490
  3. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. Gopalaswamy R, et al. FEMS Microbiol Lett, 2009 Jun. PMID 19341393
  4. Cloning, overexpression, and characterization of a serine/threonine protein kinase pknI from Mycobacterium tuberculosis H37Rv. Gopalaswamy R, et al. Protein Expr Purif, 2004 Jul. PMID 15177288
  5. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Supply P, et al. Nat Genet, 2013 Feb. PMID 23291586, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
serine/threonine protein kinase PknI
WP_003900593.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_015848.1 Reference assembly

    Range
    3280675..3282432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_003900593.1 MULTISPECIES: serine/threonine protein kinase PknI [Mycobacterium]

    See identical proteins and their annotated locations for WP_003900593.1

    UniProtKB/Swiss-Prot
    A0A1R3Y2J8, L0TB90, P65730, P65731, P9WI68, P9WI69, Q10964, X2BMF5
    UniProtKB/TrEMBL
    A0A045GSS6, A0A0H3LK47, A0A679LHS6, A0A9P2M574, A0AAE9BC15, A1KMQ8, A5U6R9
    Conserved Domains (1) summary
    cd14014
    Location:11 → 251
    STKc_PknB_like; Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins
Nucleotide Protein
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