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MT-ND1 mitochondrially encoded NADH dehydrogenase 1 [ Homo sapiens (human) ]

Gene ID: 4535, updated on 12-May-2019

Summary

Official Symbol
MT-ND1provided by HGNC
Official Full Name
mitochondrially encoded NADH dehydrogenase 1provided by HGNC
Primary source
HGNC:HGNC:7455
See related
MIM:516000
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTND1; ND1

Genomic context

See MT-ND1 in Genome Data Viewer
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) MT (non-nuclear) NC_012920.1 (3307..4262)
105 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (3307..4262)

Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene l-rRNA Neighboring gene tRNA Neighboring gene tRNA Neighboring gene tRNA Neighboring gene tRNA

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the ND1 gene: The ND1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by GOA

Function Evidence Code Pubs
NADH dehydrogenase (ubiquinone) activity NAS
Non-traceable Author Statement
more info
PubMed 
contributes_to NADH dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial electron transport, NADH to ubiquinone NAS
Non-traceable Author Statement
more info
PubMed 
mitochondrial electron transport, NADH to ubiquinone TAS
Traceable Author Statement
more info
 
mitochondrial respiratory chain complex I assembly TAS
Traceable Author Statement
more info
 
response to drug IEA
Inferred from Electronic Annotation
more info
 
response to hydroperoxide IEA
Inferred from Electronic Annotation
more info
 
response to organic cyclic compound IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
dendrite IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane TAS
Traceable Author Statement
more info
 
mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial respiratory chain complex I IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial respiratory chain complex I NAS
Non-traceable Author Statement
more info
PubMed 
neuronal cell body IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NADH dehydrogenase, subunit 1 (complex I)
Names
NADH dehydrogenase subunit 1
YP_003024026.1
  • TAA stop codon is completed by the addition of 3' A residues to the mRNA

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012920.1 Reference assembly

    Range
    3307..4262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_003024026.1 NADH dehydrogenase subunit 1 (mitochondrion) [Homo sapiens]

    See identical proteins and their annotated locations for YP_003024026.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03886
    UniProtKB/TrEMBL
    U5Z754
    Conserved Domains (1) summary
    MTH00104
    Location:1318
    ND1; NADH dehydrogenase subunit 1; Provisional
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