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PGAM4 phosphoglycerate mutase family member 4 [ Homo sapiens (human) ]

Gene ID: 441531, updated on 15-Jun-2019

Summary

Official Symbol
PGAM4provided by HGNC
Official Full Name
phosphoglycerate mutase family member 4provided by HGNC
Primary source
HGNC:HGNC:21731
See related
Ensembl:ENSG00000226784 MIM:300567
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PGAM1; PGAM3; PGAM-B; dJ1000K24.1
Summary
This intronless gene appears to have arisen from a retrotransposition event, yet it is thought to be an expressed, protein-coding gene. The encoded protein is a member of the phosphoglycerate mutase family, a set of enzymes that catalyze the transfer of a phosphate group from 3-phosphoglycerate to 2-phosphoglycerate. [provided by RefSeq, May 2010]
Orthologs

Genomic context

See PGAM4 in Genome Data Viewer
Location:
Xq21.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) X NC_000023.11 (77967961..77969638, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (77223458..77225135, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 7B Neighboring gene ATPase copper transporting alpha Neighboring gene chromosome 4 open reading frame 46 pseudogene Neighboring gene phosphoglycerate kinase 1 Neighboring gene TATA-box binding protein associated factor 9b

Genomic regions, transcripts, and products

Bibliography

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
bisphosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoglycerate mutase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphoglycerate mutase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
glycolytic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycolytic process NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of flagellated sperm motility NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
sperm principal piece IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
phosphoglycerate mutase 4
Names
phosphoglycerate mutase family 3
phosphoglycerate mutase processed protein
probable phosphoglycerate mutase 4
NP_001025062.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021360.1 RefSeqGene

    Range
    5001..6678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029891.3NP_001025062.1  phosphoglycerate mutase 4

    See identical proteins and their annotated locations for NP_001025062.1

    Status: REVIEWED

    Source sequence(s)
    AF465731, AL772330, BG875904, U76194
    Consensus CDS
    CCDS35338.1
    UniProtKB/Swiss-Prot
    Q8N0Y7
    Related
    ENSP00000412189.1, ENST00000458128.2
    Conserved Domains (1) summary
    PRK14115
    Location:4253
    gpmA; phosphoglyceromutase; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    77967949..77969638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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