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ANKRD18B ankyrin repeat domain 18B [ Homo sapiens (human) ]

Gene ID: 441459, updated on 17-Aug-2021

Summary

Official Symbol
ANKRD18Bprovided by HGNC
Official Full Name
ankyrin repeat domain 18Bprovided by HGNC
Primary source
HGNC:HGNC:23644
See related
Ensembl:ENSG00000230453 MIM:618930
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
bA255A11.3; bA255A11.5
Expression
Biased expression in testis (RPKM 1.7), skin (RPKM 0.7) and 6 other tissues See more
Orthologs
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Genomic context

See ANKRD18B in Genome Data Viewer
Location:
9p13.3
Exon count:
22
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (33524251..33575442)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (33524249..33575440)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene SUGT1 pseudogene 1 Neighboring gene vomeronasal 1 receptor 47 pseudogene Neighboring gene melanoma antigen pseudogene Neighboring gene sorting nexin 18 pseudogene 7 Neighboring gene cytochrome P450 family 4 subfamily F member 26, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
ankyrin repeat domain-containing protein 18B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353432.2NP_001340361.1  ankyrin repeat domain-containing protein 18B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL139008, BC009440, BF103989, DB512460, DW421358, DW441346
    Conserved Domains (6) summary
    cd00204
    Location:62187
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:6998
    ANK; ANK repeat [structural motif]
    pfam12001
    Location:873977
    DUF3496; Domain of unknown function (DUF3496)
    pfam13637
    Location:3488
    Ank_4; Ankyrin repeats (many copies)
    pfam14915
    Location:335625
    CCDC144C; CCDC144C protein coiled-coil region
    cl25732
    Location:468918
    SMC_N; RecF/RecN/SMC N terminal domain
  2. NM_001393611.1NP_001380540.1  ankyrin repeat domain-containing protein 18B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL139008
    Related
    ENSP00000290943.6, ENST00000290943.10
    Conserved Domains (4) summary
    COG0419
    Location:401993
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG0666
    Location:62225
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:6998
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:3488
    Ank_4; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    33524251..33575442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001013728.1: Suppressed sequence

    Description
    NM_001013728.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  2. NM_001244752.1: Suppressed sequence

    Description
    NM_001244752.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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