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SPDYE2 speedy/RINGO cell cycle regulator family member E2 [ Homo sapiens (human) ]

Gene ID: 441273, updated on 26-Oct-2022

Summary

Official Symbol
SPDYE2provided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member E2provided by HGNC
Primary source
HGNC:HGNC:33841
See related
Ensembl:ENSG00000205238 MIM:617624; AllianceGenome:HGNC:33841
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPDYB2L1; SPDYB2-L1
Summary
Predicted to enable protein kinase binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 4.7), spleen (RPKM 2.6) and 24 other tissues See more
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Genomic context

See SPDYE2 in Genome Data Viewer
Location:
7q22.1
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (102551226..102565227)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (103868752..103881058)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (102191673..102203985)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene RAS p21 protein activator 4B Neighboring gene Sharpr-MPRA regulatory region 3260 Neighboring gene POLR2J3-UPK3BL2 readthrough Neighboring gene uroplakin 3B like 2 Neighboring gene uncharacterized LOC124901712 Neighboring gene RNA polymerase II subunit J3 Neighboring gene RAS p21 protein activator 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
speedy protein E2
Names
Speedy B2-like 1
putative Speedy protein E2
speedy homolog E2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031618.3NP_001026789.2  speedy protein E2

    See identical proteins and their annotated locations for NP_001026789.2

    Status: VALIDATED

    Source sequence(s)
    AC093668, AK302217, BF809327, DR731150
    Consensus CDS
    CCDS34716.2
    UniProtKB/Swiss-Prot
    B4DY11, Q495Y8
    UniProtKB/TrEMBL
    I6XC90
    Related
    ENSP00000421686.1, ENST00000507918.6
    Conserved Domains (1) summary
    pfam11357
    Location:194398
    Spy1; Cell cycle regulatory protein
  2. NM_001396242.1NP_001383171.1  speedy protein E2

    Status: VALIDATED

    Source sequence(s)
    AC093668
    Consensus CDS
    CCDS34716.2
    UniProtKB/Swiss-Prot
    B4DY11
    UniProtKB/TrEMBL
    I6XC90
    Related
    ENSP00000509749.1, ENST00000691607.2
    Conserved Domains (1) summary
    pfam11357
    Location:194398
    Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    102551226..102565227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011516237.4XP_011514539.1  speedy protein E2 isoform X1

    Conserved Domains (1) summary
    pfam11357
    Location:194303
    Spy1; Cell cycle regulatory protein
  2. XM_047420405.1XP_047276361.1  speedy protein E2 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    103868752..103881058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)