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TMEM89 transmembrane protein 89 [ Homo sapiens (human) ]

Gene ID: 440955, updated on 5-Mar-2024

Summary

Official Symbol
TMEM89provided by HGNC
Official Full Name
transmembrane protein 89provided by HGNC
Primary source
HGNC:HGNC:32372
See related
Ensembl:ENSG00000183396 AllianceGenome:HGNC:32372
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 5.1) See more
Orthologs
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Genomic context

See TMEM89 in Genome Data Viewer
Location:
3p21.31
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (48620759..48621769, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (48649719..48650729, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (48658192..48659202, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene collagen type VII alpha 1 chain Neighboring gene microRNA 711 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48625763-48626466 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48626467-48627168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48638465-48638965 Neighboring gene ubiquinol-cytochrome c reductase core protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14334 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19838 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:48647149-48647663 Neighboring gene small nucleolar RNA, H/ACA box 94 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48651179-48651678 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48666910-48667410 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48667411-48667911 Neighboring gene solute carrier family 26 member 6 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14335 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14336 Neighboring gene microRNA 6824 Neighboring gene cadherin EGF LAG seven-pass G-type receptor 3 Neighboring gene microRNA 4793

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008269.3NP_001008270.1  transmembrane protein 89 precursor

    See identical proteins and their annotated locations for NP_001008270.1

    Status: VALIDATED

    Source sequence(s)
    BC133036
    Consensus CDS
    CCDS33751.1
    UniProtKB/Swiss-Prot
    A2RUT3
    Related
    ENSP00000329557.3, ENST00000330862.4
    Conserved Domains (1) summary
    pfam15098
    Location:23156
    TMEM89; TMEM89 protein family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    48620759..48621769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    48649719..48650729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)