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LRRC52 leucine rich repeat containing 52 [ Homo sapiens (human) ]

Gene ID: 440699, updated on 22-Jun-2021

Summary

Official Symbol
LRRC52provided by HGNC
Official Full Name
leucine rich repeat containing 52provided by HGNC
Primary source
HGNC:HGNC:32156
See related
Ensembl:ENSG00000162763 MIM:615218
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 7.8) See more
Orthologs
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Genomic context

See LRRC52 in Genome Data Viewer
Location:
1q24.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (165544000..165563957)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (165513237..165533194)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene retinoid X receptor gamma Neighboring gene LRRC52 antisense RNA 1 Neighboring gene PRELID1 pseudogene 7 Neighboring gene ribosomal protein S2 pseudogene 10 Neighboring gene tRNA-Lys (anticodon CTT) 13-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25811

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables potassium channel activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables potassium channel activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane transporter binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables voltage-gated potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables voltage-gated potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of voltage-gated potassium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of voltage-gated potassium channel complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
leucine-rich repeat-containing protein 52
Names
BK channel auxiliary gamma subunit LRRC52
BK channel auxilliary gamma subunit LRRC52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005214.4NP_001005214.2  leucine-rich repeat-containing protein 52 precursor

    See identical proteins and their annotated locations for NP_001005214.2

    Status: VALIDATED

    Source sequence(s)
    AL157714
    Consensus CDS
    CCDS30930.1
    UniProtKB/Swiss-Prot
    Q8N7C0
    Related
    ENSP00000294818.2, ENST00000294818.2
    Conserved Domains (4) summary
    PRK15387
    Location:293
    PRK15387; type III secretion system effector E3 ubiquitin transferase SspH2
    smart00013
    Location:2655
    LRRNT; Leucine rich repeat N-terminal domain
    sd00033
    Location:3554
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:79136
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    165544000..165563957
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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