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PRAMEF11 PRAME family member 11 [ Homo sapiens (human) ]

Gene ID: 440560, updated on 5-Aug-2022

Summary

Official Symbol
PRAMEF11provided by HGNC
Official Full Name
PRAME family member 11provided by HGNC
Primary source
HGNC:HGNC:14086
See related
Ensembl:ENSG00000239810 AllianceGenome:HGNC:14086
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See PRAMEF11 in Genome Data Viewer
Location:
1p36.21
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (12824605..12831410, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12368616..12375422, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (12884463..12891264, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 1 Neighboring gene long intergenic non-protein coding RNA 1784 Neighboring gene PRAME family member 30, pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein C like 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146344.3NP_001139816.2  PRAME family member 11

    See identical proteins and their annotated locations for NP_001139816.2

    Status: VALIDATED

    Source sequence(s)
    AC245034
    Consensus CDS
    CCDS53268.2
    UniProtKB/Swiss-Prot
    B7ZMC2
    UniProtKB/TrEMBL
    A0A087WW85
    Related
    ENSP00000480027.2, ENST00000619922.1
    Conserved Domains (1) summary
    cd21340
    Location:269393
    PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    12824605..12831410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541479.3XP_011539781.1  PRAME family member 11 isoform X1

    See identical proteins and their annotated locations for XP_011539781.1

    UniProtKB/Swiss-Prot
    B7ZMC2
    UniProtKB/TrEMBL
    A0A087WW85
    Conserved Domains (1) summary
    cd21340
    Location:269393
    PPP1R42; protein phosphatase 1 regulatory subunit 42

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132914.1 Reference GRCh38.p14 PATCHES

    Range
    6118..12923 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    12368616..12375422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)