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C2 complement C2 [ Gallus gallus (chicken) ]

Gene ID: 419574, updated on 17-Aug-2024

Summary

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Symbol
C2provided by CGNC
Full Name
complement C2provided by CGNC
Primary source
CGNC:17285
See related
Ensembl:ENSGALG00010013989
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 23 NC_052554.1 (2142468..2148760, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 23 NC_052595.1 (1911346..1917633, complement)

Chromosome 23 - NC_052554.1Genomic Context describing neighboring genes Neighboring gene zinc metallopeptidase STE24 Neighboring gene rearranged L-myc fusion Neighboring gene zinc finger, DHHC-type containing 18 Neighboring gene stratifin Neighboring gene GPN-loop GTPase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement C2
Names
complement component 2
XP_040546037.1
XP_417722.7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052554.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2142468..2148760 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_417722.8 → XP_417722.7  complement C2

    UniProtKB/TrEMBL
    A0A8V0YU75
    Related
    ENSGALP00010019772.1, ENSGALT00010033541.1
    Conserved Domains (4) summary
    cd00033
    Location:59 → 114
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02927
    Location:54 → 174
    PHA02927; secreted complement-binding protein; Provisional
    cl00057
    Location:223 → 422
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21584
    Location:446 → 709
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052595.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1911346..1917633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040690103.2 → XP_040546037.1  complement C2

    UniProtKB/TrEMBL
    A0A8V0YU75
    Conserved Domains (4) summary
    cd00033
    Location:59 → 114
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02927
    Location:54 → 174
    PHA02927; secreted complement-binding protein; Provisional
    cl00057
    Location:223 → 422
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21584
    Location:446 → 709
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
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