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CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Gallus gallus (chicken) ]

Gene ID: 417900, updated on 17-Aug-2024

Summary

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Symbol
CRADDprovided by CGNC
Full Name
CASP2 and RIPK1 domain containing adaptor with death domainprovided by CGNC
Primary source
CGNC:8588
See related
Ensembl:ENSGALG00010010466
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (44954169..45032103)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (45305219..45383130)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052984 Neighboring gene mitochondrial ribosomal protein L42 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC112533381 Neighboring gene suppressor of cytokine signaling 2 Neighboring gene myosin heavy chain IB-like Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene plexin C1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables death domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
death domain-containing protein CRADD

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030748.2 → NP_001025919.1  death domain-containing protein CRADD isoform b

    See identical proteins and their annotated locations for NP_001025919.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    Q5F3I3
    Related
    ENSGALP00010014222.1, ENSGALT00010025019.1
    Conserved Domains (2) summary
    cd08319
    Location:114 → 196
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  2. NM_001397043.1 → NP_001383972.1  death domain-containing protein CRADD isoform a

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    A0A8V0Y761
    Related
    ENSGALP00010014220.1, ENSGALT00010025017.1
    Conserved Domains (2) summary
    cd08319
    Location:171 → 253
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  3. NM_001397044.1 → NP_001383973.1  death domain-containing protein CRADD isoform b

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    Q5F3I3
    Conserved Domains (2) summary
    cd08319
    Location:114 → 196
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  4. NM_001397045.1 → NP_001383974.1  death domain-containing protein CRADD isoform b

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    Q5F3I3
    Conserved Domains (2) summary
    cd08319
    Location:114 → 196
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    44954169..45032103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040695938.2 → XP_040551872.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761
    Conserved Domains (2) summary
    cd08319
    Location:171 → 253
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  2. XM_040695932.2 → XP_040551866.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761
    Conserved Domains (2) summary
    cd08319
    Location:171 → 253
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  3. XM_040695934.2 → XP_040551868.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761
    Conserved Domains (2) summary
    cd08319
    Location:171 → 253
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

  4. XM_040695936.2 → XP_040551870.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761
    Conserved Domains (2) summary
    cd08319
    Location:171 → 253
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:1 → 94
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    45305219..45383130
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907337.1 → XP_046763293.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761

  2. XM_046907334.1 → XP_046763290.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761

  3. XM_046907335.1 → XP_046763291.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761

  4. XM_046907336.1 → XP_046763292.1  death domain-containing protein CRADD isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y761
Nucleotide Protein Strain
Heading Accession and Version

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