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MBD1 methyl-CpG binding domain protein 1 [ Homo sapiens (human) ]

Gene ID: 4152, updated on 6-Nov-2022

Summary

Official Symbol
MBD1provided by HGNC
Official Full Name
methyl-CpG binding domain protein 1provided by HGNC
Primary source
HGNC:HGNC:6916
See related
Ensembl:ENSG00000141644 MIM:156535; AllianceGenome:HGNC:6916
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RFT; PCM1; CXXC3
Summary
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
Expression
Ubiquitous expression in testis (RPKM 18.8), bone marrow (RPKM 9.7) and 25 other tissues See more
Orthologs
NEW
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Try the new Transcript table

Genomic context

See MBD1 in Genome Data Viewer
Location:
18q21.1
Exon count:
20
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (50266885..50281767, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (50468627..50483509, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (47793255..47808137, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 310, pseudogene Neighboring gene cilia and flagella associated protein 53 Neighboring gene uncharacterized LOC124904300 Neighboring gene CXXC finger protein 1 Neighboring gene uncharacterized LOC124904301

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding TAS
Traceable Author Statement
more info
PubMed 
enables double-stranded methylated DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables methyl-CpG binding IDA
Inferred from Direct Assay
more info
PubMed 
enables methyl-CpG binding NAS
Non-traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables unmethylated CpG binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear matrix ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nuclear speck ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
methyl-CpG-binding domain protein 1
Names
CXXC-type zinc finger protein 3
protein containing methyl-CpG-binding domain 1
the regulator of fibroblast growth factor 2 (FGF-2) transcription

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029505.1 RefSeqGene

    Range
    5252..17929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001204136.2NP_001191065.1  methyl-CpG-binding domain protein 1 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks the penultimate exon compared to variant 1. This results in a frame-shift, and a longer isoform (6) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AJ564845, AK225889, AK291519, AK302004, CD723822
    Consensus CDS
    CCDS59320.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654
    Related
    ENSP00000468785.1, ENST00000590208.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  2. NM_001204137.2NP_001191066.1  methyl-CpG-binding domain protein 1 isoform 7

    See identical proteins and their annotated locations for NP_001191066.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) contains an additional in-frame coding exon, and has a different 3' UTR compared to variant 1. This results in a longer isoform (7, also known as RFT-A) with an extra protein segment not found in isoform 1. This isoform has been shown to repress FGF-2 expression at the transcriptional level, and may be involved in FGF-2-dependent tumor progression (PMID:10187827).
    Source sequence(s)
    AC090246, AK291519, AK295401, AK302004, BP384783
    Consensus CDS
    CCDS56073.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654, B4DI41
    Related
    ENSP00000405268.2, ENST00000457839.6
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  3. NM_001204138.2NP_001191067.1  methyl-CpG-binding domain protein 1 isoform 8

    See identical proteins and their annotated locations for NP_001191067.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) is the same as variant 7, except uses an alternate acceptor splice site at one of the coding exons, resulting in an isoform (8, also known as RFT-Aprime) that is 1 aa shorter than isoform 7. Unlike isoform 7, this isoform fails to bind FGF-2 promoter and repress FGF-2 gene expression (PMID:10187827).
    Source sequence(s)
    AC090246, AK291519, AK295401, AK302004, BP384783
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654, B4DI41
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  4. NM_001204139.2NP_001191068.1  methyl-CpG-binding domain protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001191068.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) contains an alternate 3' terminal non-coding exon, thus has a different 3' UTR compared to variant 1. Variants 1 and 14 encode the same isoform (1).
    Source sequence(s)
    AK291519, AK302004, BC047353
    Consensus CDS
    CCDS11943.1
    UniProtKB/Swiss-Prot
    Q9UIS9, Q9UNZ9
    UniProtKB/TrEMBL
    A8K654
    Related
    ENSP00000372407.5, ENST00000382948.9
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  5. NM_001204140.2NP_001191069.1  methyl-CpG-binding domain protein 1 isoform 9

    See identical proteins and their annotated locations for NP_001191069.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) is the same as variant 7, except lacks an in-frame coding exon, resulting in an isoform (9, also known as RFT-B) that is missing an internal protein segment compared to isoform 7. Unlike isoform 7, this isoform fails to bind FGF-2 promoter and repress FGF-2 gene expression (PMID:10187827).
    Source sequence(s)
    AC090246, AK291519, AK295401, AK302004, BP384783
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654, B4DI41
    Related
    ENSP00000381508.2, ENST00000398495.6
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  6. NM_001204141.2NP_001191070.1  methyl-CpG-binding domain protein 1 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) lacks 2 non-consecutive coding exons, and contains an alternate 3' terminal exon compared to variant 1. This results in a frame-shift in the 3' coding region, and a shorter isoform (10) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK225889, AK291519, AK302004, BC047353
    Consensus CDS
    CCDS59318.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654
    Related
    ENSP00000466092.1, ENST00000585672.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:281327
    zf-CXXC; CXXC zinc finger domain
  7. NM_001204142.2NP_001191071.1  methyl-CpG-binding domain protein 1 isoform 11

    See identical proteins and their annotated locations for NP_001191071.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) lacks 3 non-consecutive coding exons, and uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1. This results in a frame-shift in the 3' coding region, and a shorter isoform (11) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AF078831, AJ564845, AK291519, CD723822
    Consensus CDS
    CCDS56072.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    A8K654
    Related
    ENSP00000339546.5, ENST00000339998.10
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  8. NM_001204143.2NP_001191072.1  methyl-CpG-binding domain protein 1 isoform 12

    See identical proteins and their annotated locations for NP_001191072.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) lacks 3 non-consecutive coding exons, and uses an alternate donor splice site at the 5' non-coding exon and an alternate acceptor splice site at the 3' terminal exon compared to variant 1. This results in a frame-shift in the 3' coding region, and a shorter isoform (12) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AF078831, AJ564845, AK300759, CD723822
    Consensus CDS
    CCDS59319.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    UniProtKB/TrEMBL
    B4DUR3
    Related
    ENSP00000468042.1, ENST00000587605.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  9. NM_001204151.3NP_001191080.1  methyl-CpG-binding domain protein 1 isoform 13

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13) lacks 2 non-consecutive in-frame coding exons compared to variant 1. This results in a shorter isoform (13) missing two internal protein segments compared to isoform 1.
    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS56071.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    Related
    ENSP00000465923.1, ENST00000591535.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:308354
    zf-CXXC; CXXC zinc finger domain
  10. NM_001323942.2NP_001310871.1  methyl-CpG-binding domain protein 1 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS92462.1
    Related
    ENSP00000516153.1, ENST00000705655.1
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  11. NM_001323947.2NP_001310876.1  methyl-CpG-binding domain protein 1 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  12. NM_001323949.2NP_001310878.1  methyl-CpG-binding domain protein 1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC090246
  13. NM_001323950.2NP_001310879.1  methyl-CpG-binding domain protein 1 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC090246
  14. NM_001323951.2NP_001310880.1  methyl-CpG-binding domain protein 1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC090246
  15. NM_001323952.2NP_001310881.1  methyl-CpG-binding domain protein 1 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC090246
  16. NM_001323953.2NP_001310882.1  methyl-CpG-binding domain protein 1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC090246
  17. NM_001323954.2NP_001310883.1  methyl-CpG-binding domain protein 1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  18. NM_001388138.1NP_001375067.1  methyl-CpG-binding domain protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11943.1
    UniProtKB/Swiss-Prot
    Q9UNZ9
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  19. NM_001388139.1NP_001375068.1  methyl-CpG-binding domain protein 1 isoform 42

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  20. NM_001388140.1NP_001375069.1  methyl-CpG-binding domain protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS56073.1
    Related
    ENSP00000468430.1, ENST00000585595.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  21. NM_001388141.1NP_001375070.1  methyl-CpG-binding domain protein 1 isoform 43

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:355401
    zf-CXXC; CXXC zinc finger domain
  22. NM_001388142.1NP_001375071.1  methyl-CpG-binding domain protein 1 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  23. NM_001388143.1NP_001375072.1  methyl-CpG-binding domain protein 1 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  24. NM_001388144.1NP_001375073.1  methyl-CpG-binding domain protein 1 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS59319.1
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  25. NM_001388145.1NP_001375074.1  methyl-CpG-binding domain protein 1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  26. NM_001388146.1NP_001375075.1  methyl-CpG-binding domain protein 1 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  27. NM_001388147.1NP_001375076.1  methyl-CpG-binding domain protein 1 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  28. NM_001388148.1NP_001375077.1  methyl-CpG-binding domain protein 1 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  29. NM_001388149.1NP_001375078.1  methyl-CpG-binding domain protein 1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  30. NM_001388150.1NP_001375079.1  methyl-CpG-binding domain protein 1 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  31. NM_001388151.1NP_001375080.1  methyl-CpG-binding domain protein 1 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  32. NM_001388152.1NP_001375081.1  methyl-CpG-binding domain protein 1 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  33. NM_001388153.1NP_001375082.1  methyl-CpG-binding domain protein 1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  34. NM_001388154.1NP_001375083.1  methyl-CpG-binding domain protein 1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  35. NM_001388155.1NP_001375084.1  methyl-CpG-binding domain protein 1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  36. NM_001388156.1NP_001375085.1  methyl-CpG-binding domain protein 1 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  37. NM_001388157.1NP_001375086.1  methyl-CpG-binding domain protein 1 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  38. NM_001388158.1NP_001375087.1  methyl-CpG-binding domain protein 1 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  39. NM_001388159.1NP_001375088.1  methyl-CpG-binding domain protein 1 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  40. NM_001388160.1NP_001375089.1  methyl-CpG-binding domain protein 1 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  41. NM_001388161.1NP_001375090.1  methyl-CpG-binding domain protein 1 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  42. NM_001388162.1NP_001375091.1  methyl-CpG-binding domain protein 1 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  43. NM_001388163.1NP_001375092.1  methyl-CpG-binding domain protein 1 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  44. NM_001388164.1NP_001375093.1  methyl-CpG-binding domain protein 1 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  45. NM_001388165.1NP_001375094.1  methyl-CpG-binding domain protein 1 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  46. NM_001388166.1NP_001375095.1  methyl-CpG-binding domain protein 1 isoform 40

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  47. NM_001388167.1NP_001375096.1  methyl-CpG-binding domain protein 1 isoform 41

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  48. NM_001399879.1NP_001386808.1  methyl-CpG-binding domain protein 1 isoform 45

    Status: REVIEWED

    Source sequence(s)
    AC090246
  49. NM_001399880.1NP_001386809.1  methyl-CpG-binding domain protein 1 isoform 46

    Status: REVIEWED

    Source sequence(s)
    AC090246
    UniProtKB/TrEMBL
    B4DI41
  50. NM_001399881.1NP_001386810.1  methyl-CpG-binding domain protein 1 isoform 47

    Status: REVIEWED

    Source sequence(s)
    AC090246
  51. NM_001399882.1NP_001386811.1  methyl-CpG-binding domain protein 1 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AC090246
  52. NM_001399883.1NP_001386812.1  methyl-CpG-binding domain protein 1 isoform 49

    Status: REVIEWED

    Source sequence(s)
    AC090246
  53. NM_001399884.1NP_001386813.1  methyl-CpG-binding domain protein 1 isoform 50

    Status: REVIEWED

    Source sequence(s)
    AC090246
  54. NM_001399885.1NP_001386814.1  methyl-CpG-binding domain protein 1 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC090246
  55. NM_001399886.1NP_001386815.1  methyl-CpG-binding domain protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS56073.1
  56. NM_001399887.1NP_001386816.1  methyl-CpG-binding domain protein 1 isoform 52

    Status: REVIEWED

    Source sequence(s)
    AC090246
  57. NM_001399888.1NP_001386817.1  methyl-CpG-binding domain protein 1 isoform 43

    Status: REVIEWED

    Source sequence(s)
    AC090246
  58. NM_001399889.1NP_001386818.1  methyl-CpG-binding domain protein 1 isoform 53

    Status: REVIEWED

    Source sequence(s)
    AC090246
  59. NM_001399890.1NP_001386819.1  methyl-CpG-binding domain protein 1 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC090246
  60. NM_001399891.1NP_001386820.1  methyl-CpG-binding domain protein 1 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AC090246
  61. NM_001399892.1NP_001386821.1  methyl-CpG-binding domain protein 1 isoform 56

    Status: REVIEWED

    Source sequence(s)
    AC090246
  62. NM_001399893.1NP_001386822.1  methyl-CpG-binding domain protein 1 isoform 57

    Status: REVIEWED

    Source sequence(s)
    AC090246
  63. NM_001399894.1NP_001386823.1  methyl-CpG-binding domain protein 1 isoform 58

    Status: REVIEWED

    Source sequence(s)
    AC090246
  64. NM_001399895.1NP_001386824.1  methyl-CpG-binding domain protein 1 isoform 59

    Status: REVIEWED

    Source sequence(s)
    AC090246
  65. NM_001399896.1NP_001386825.1  methyl-CpG-binding domain protein 1 isoform 60

    Status: REVIEWED

    Source sequence(s)
    AC090246
  66. NM_001399897.1NP_001386826.1  methyl-CpG-binding domain protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11943.1
    UniProtKB/Swiss-Prot
    Q9UNZ9
  67. NM_001399898.1NP_001386827.1  methyl-CpG-binding domain protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11943.1
    UniProtKB/Swiss-Prot
    Q9UNZ9
  68. NM_001399899.1NP_001386828.1  methyl-CpG-binding domain protein 1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC090246
  69. NM_001399900.1NP_001386829.1  methyl-CpG-binding domain protein 1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC090246
  70. NM_001399901.1NP_001386830.1  methyl-CpG-binding domain protein 1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC090246
  71. NM_001399902.1NP_001386831.1  methyl-CpG-binding domain protein 1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC090246
  72. NM_001399903.1NP_001386832.1  methyl-CpG-binding domain protein 1 isoform 62

    Status: REVIEWED

    Source sequence(s)
    AC090246
  73. NM_001399904.1NP_001386833.1  methyl-CpG-binding domain protein 1 isoform 63

    Status: REVIEWED

    Source sequence(s)
    AC090246
  74. NM_001399905.1NP_001386834.1  methyl-CpG-binding domain protein 1 isoform 64

    Status: REVIEWED

    Source sequence(s)
    AC090246
  75. NM_001399906.1NP_001386835.1  methyl-CpG-binding domain protein 1 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC090246
  76. NM_001399907.1NP_001386836.1  methyl-CpG-binding domain protein 1 isoform 66

    Status: REVIEWED

    Source sequence(s)
    AC090246
  77. NM_001399908.1NP_001386837.1  methyl-CpG-binding domain protein 1 isoform 67

    Status: REVIEWED

    Source sequence(s)
    AC090246
  78. NM_001399909.1NP_001386838.1  methyl-CpG-binding domain protein 1 isoform 68

    Status: REVIEWED

    Source sequence(s)
    AC090246
  79. NM_001399910.1NP_001386839.1  methyl-CpG-binding domain protein 1 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC090246
  80. NM_001399911.1NP_001386840.1  methyl-CpG-binding domain protein 1 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC090246
  81. NM_001399912.1NP_001386841.1  methyl-CpG-binding domain protein 1 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC090246
  82. NM_001399913.1NP_001386842.1  methyl-CpG-binding domain protein 1 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC090246
  83. NM_001399914.1NP_001386843.1  methyl-CpG-binding domain protein 1 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC090246
  84. NM_001399915.1NP_001386844.1  methyl-CpG-binding domain protein 1 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC090246
  85. NM_001399916.1NP_001386845.1  methyl-CpG-binding domain protein 1 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC090246
  86. NM_001399917.1NP_001386846.1  methyl-CpG-binding domain protein 1 isoform 72

    Status: REVIEWED

    Source sequence(s)
    AC090246
  87. NM_001399918.1NP_001386847.1  methyl-CpG-binding domain protein 1 isoform 73

    Status: REVIEWED

    Source sequence(s)
    AC090246
  88. NM_001399919.1NP_001386848.1  methyl-CpG-binding domain protein 1 isoform 74

    Status: REVIEWED

    Source sequence(s)
    AC090246
  89. NM_001399920.1NP_001386849.1  methyl-CpG-binding domain protein 1 isoform 75

    Status: REVIEWED

    Source sequence(s)
    AC090246
  90. NM_001399921.1NP_001386850.1  methyl-CpG-binding domain protein 1 isoform 76

    Status: REVIEWED

    Source sequence(s)
    AC090246
  91. NM_001399922.1NP_001386851.1  methyl-CpG-binding domain protein 1 isoform 77

    Status: REVIEWED

    Source sequence(s)
    AC090246
  92. NM_001399923.1NP_001386852.1  methyl-CpG-binding domain protein 1 isoform 78

    Status: REVIEWED

    Source sequence(s)
    AC090246
  93. NM_001399924.1NP_001386853.1  methyl-CpG-binding domain protein 1 isoform 79

    Status: REVIEWED

    Source sequence(s)
    AC090246
  94. NM_001399925.1NP_001386854.1  methyl-CpG-binding domain protein 1 isoform 80

    Status: REVIEWED

    Source sequence(s)
    AC090246
  95. NM_001399926.1NP_001386855.1  methyl-CpG-binding domain protein 1 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC090246
  96. NM_001399927.1NP_001386856.1  methyl-CpG-binding domain protein 1 isoform 82

    Status: REVIEWED

    Source sequence(s)
    AC090246
  97. NM_001399928.1NP_001386857.1  methyl-CpG-binding domain protein 1 isoform 83

    Status: REVIEWED

    Source sequence(s)
    AC090246
  98. NM_001399929.1NP_001386858.1  methyl-CpG-binding domain protein 1 isoform 84

    Status: REVIEWED

    Source sequence(s)
    AC090246
  99. NM_001399930.1NP_001386859.1  methyl-CpG-binding domain protein 1 isoform 85

    Status: REVIEWED

    Source sequence(s)
    AC090246
  100. NM_001399931.1NP_001386860.1  methyl-CpG-binding domain protein 1 isoform 86

    Status: REVIEWED

    Source sequence(s)
    AC090246
  101. NM_001399932.1NP_001386861.1  methyl-CpG-binding domain protein 1 isoform 87

    Status: REVIEWED

    Source sequence(s)
    AC090246
  102. NM_001399933.1NP_001386862.1  methyl-CpG-binding domain protein 1 isoform 88

    Status: REVIEWED

    Source sequence(s)
    AC090246
  103. NM_001399934.1NP_001386863.1  methyl-CpG-binding domain protein 1 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC090246
  104. NM_001399935.1NP_001386864.1  methyl-CpG-binding domain protein 1 isoform 89

    Status: REVIEWED

    Source sequence(s)
    AC090246
  105. NM_001399936.1NP_001386865.1  methyl-CpG-binding domain protein 1 isoform 90

    Status: REVIEWED

    Source sequence(s)
    AC090246
  106. NM_001399937.1NP_001386866.1  methyl-CpG-binding domain protein 1 isoform 91

    Status: REVIEWED

    Source sequence(s)
    AC090246
  107. NM_001399938.1NP_001386867.1  methyl-CpG-binding domain protein 1 isoform 92

    Status: REVIEWED

    Source sequence(s)
    AC090246
  108. NM_001399939.1NP_001386868.1  methyl-CpG-binding domain protein 1 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC090246
  109. NM_001399940.1NP_001386869.1  methyl-CpG-binding domain protein 1 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC090246
  110. NM_001399941.1NP_001386870.1  methyl-CpG-binding domain protein 1 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11942.1
  111. NM_001399942.1NP_001386871.1  methyl-CpG-binding domain protein 1 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11942.1
  112. NM_001399943.1NP_001386872.1  methyl-CpG-binding domain protein 1 isoform 94

    Status: REVIEWED

    Source sequence(s)
    AC090246
  113. NM_001399944.1NP_001386873.1  methyl-CpG-binding domain protein 1 isoform 95

    Status: REVIEWED

    Source sequence(s)
    AC090246
  114. NM_001399945.1NP_001386874.1  methyl-CpG-binding domain protein 1 isoform 96

    Status: REVIEWED

    Source sequence(s)
    AC090246
  115. NM_001399946.1NP_001386875.1  methyl-CpG-binding domain protein 1 isoform 97

    Status: REVIEWED

    Source sequence(s)
    AC090246
  116. NM_001399947.1NP_001386876.1  methyl-CpG-binding domain protein 1 isoform 98

    Status: REVIEWED

    Source sequence(s)
    AC090246
  117. NM_001399948.1NP_001386877.1  methyl-CpG-binding domain protein 1 isoform 98

    Status: REVIEWED

    Source sequence(s)
    AC090246
  118. NM_001399949.1NP_001386878.1  methyl-CpG-binding domain protein 1 isoform 99

    Status: REVIEWED

    Source sequence(s)
    AC090246
  119. NM_001399950.1NP_001386879.1  methyl-CpG-binding domain protein 1 isoform 100

    Status: REVIEWED

    Source sequence(s)
    AC090246
  120. NM_001399952.1NP_001386881.1  methyl-CpG-binding domain protein 1 isoform 101

    Status: REVIEWED

    Source sequence(s)
    AC090246
  121. NM_001399953.1NP_001386882.1  methyl-CpG-binding domain protein 1 isoform 102

    Status: REVIEWED

    Source sequence(s)
    AC090246
  122. NM_001399954.1NP_001386883.1  methyl-CpG-binding domain protein 1 isoform 103

    Status: REVIEWED

    Source sequence(s)
    AC090246
  123. NM_001399955.1NP_001386884.1  methyl-CpG-binding domain protein 1 isoform 104

    Status: REVIEWED

    Source sequence(s)
    AC090246
  124. NM_001399956.1NP_001386885.1  methyl-CpG-binding domain protein 1 isoform 105

    Status: REVIEWED

    Source sequence(s)
    AC090246
  125. NM_001399957.1NP_001386886.1  methyl-CpG-binding domain protein 1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC090246
    Consensus CDS
    CCDS11941.1
    Related
    ENSP00000381502.1, ENST00000398488.5
  126. NM_001399958.1NP_001386887.1  methyl-CpG-binding domain protein 1 isoform 106

    Status: REVIEWED

    Source sequence(s)
    AC090246
  127. NM_001399959.1NP_001386888.1  methyl-CpG-binding domain protein 1 isoform 107

    Status: REVIEWED

    Source sequence(s)
    AC090246
  128. NM_001399960.1NP_001386889.1  methyl-CpG-binding domain protein 1 isoform 108

    Status: REVIEWED

    Source sequence(s)
    AC090246
  129. NM_001399961.1NP_001386890.1  methyl-CpG-binding domain protein 1 isoform 109

    Status: REVIEWED

    Source sequence(s)
    AC090246
  130. NM_001399962.1NP_001386891.1  methyl-CpG-binding domain protein 1 isoform 110

    Status: REVIEWED

    Source sequence(s)
    AC090246
  131. NM_001399963.1NP_001386892.1  methyl-CpG-binding domain protein 1 isoform 111

    Status: REVIEWED

    Source sequence(s)
    AC090246
  132. NM_001399964.1NP_001386893.1  methyl-CpG-binding domain protein 1 isoform 111

    Status: REVIEWED

    Source sequence(s)
    AC090246
  133. NM_001399965.1NP_001386894.1  methyl-CpG-binding domain protein 1 isoform 112

    Status: REVIEWED

    Source sequence(s)
    AC090246
  134. NM_001399966.1NP_001386895.1  methyl-CpG-binding domain protein 1 isoform 113

    Status: REVIEWED

    Source sequence(s)
    AC090246
  135. NM_001399967.1NP_001386896.1  methyl-CpG-binding domain protein 1 isoform 114

    Status: REVIEWED

    Source sequence(s)
    AC090246
  136. NM_001399968.1NP_001386897.1  methyl-CpG-binding domain protein 1 isoform 114

    Status: REVIEWED

    Source sequence(s)
    AC090246
  137. NM_001399970.1NP_001386899.1  methyl-CpG-binding domain protein 1 isoform 114

    Status: REVIEWED

    Source sequence(s)
    AC090246
  138. NM_001399971.1NP_001386900.1  methyl-CpG-binding domain protein 1 isoform 115

    Status: REVIEWED

    Source sequence(s)
    AC090246
  139. NM_001399973.1NP_001386902.1  methyl-CpG-binding domain protein 1 isoform 116

    Status: REVIEWED

    Source sequence(s)
    AC090246
  140. NM_001399974.1NP_001386903.1  methyl-CpG-binding domain protein 1 isoform 117

    Status: REVIEWED

    Source sequence(s)
    AC090246
  141. NM_001399975.1NP_001386904.1  methyl-CpG-binding domain protein 1 isoform 118

    Status: REVIEWED

    Source sequence(s)
    AC090246
  142. NM_001399976.1NP_001386905.1  methyl-CpG-binding domain protein 1 isoform 119

    Status: REVIEWED

    Source sequence(s)
    AC090246
  143. NM_002384.3NP_002375.1  methyl-CpG-binding domain protein 1 isoform 4

    See identical proteins and their annotated locations for NP_002375.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks 2 in-frame non-consecutive coding exons compared to variant 1, resulting in a shorter isoform (4) missing two internal protein segments compared to isoform 1.
    Source sequence(s)
    AJ564845, AK225948, BC033242, DC403953
    Consensus CDS
    CCDS11941.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  144. NM_015844.3NP_056669.2  methyl-CpG-binding domain protein 1 isoform 3

    See identical proteins and their annotated locations for NP_056669.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1, resulting in a shorter isoform (3) missing an internal protein segment compared to isoform 1.
    Source sequence(s)
    AJ564845, AK225948, BC033242, DC403953
    Consensus CDS
    CCDS11942.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    Related
    ENSP00000285102.5, ENST00000347968.7
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  145. NM_015845.4NP_056670.2  methyl-CpG-binding domain protein 1 isoform 2

    See identical proteins and their annotated locations for NP_056670.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) is missing 3 non-consecutive coding exons compared to variant 1, the last of which causes a frame-shift. This results in a shorter isoform (2) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AJ564845, AK225889, AK225948, BC033242, DC403953
    Consensus CDS
    CCDS32832.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    Related
    ENSP00000269471.5, ENST00000269471.9
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:308354
    zf-CXXC; CXXC zinc finger domain
  146. NM_015846.4NP_056671.2  methyl-CpG-binding domain protein 1 isoform 1

    See identical proteins and their annotated locations for NP_056671.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1. Variants 1 and 14 encode the same isoform.
    Source sequence(s)
    AJ564845, AK225889, AK225948, BC033242, DC403953
    Consensus CDS
    CCDS11943.1
    UniProtKB/Swiss-Prot
    Q9UIS9, Q9UNZ9
    Related
    ENSP00000269468.5, ENST00000269468.10
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  147. NM_015847.4NP_056723.2  methyl-CpG-binding domain protein 1 isoform 5

    See identical proteins and their annotated locations for NP_056723.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks an in-frame coding exon compared to variant 1, resulting in a shorter isoform (5) missing an internal protein segment compared to isoform 1.
    Source sequence(s)
    AJ564845, AK225889, AK225948, BC033242, DC403953
    Consensus CDS
    CCDS11944.1
    UniProtKB/Swiss-Prot
    Q9UIS9
    Related
    ENSP00000269469.5, ENST00000353909.7
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:282328
    zf-CXXC; CXXC zinc finger domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    50266885..50281767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047437514.1XP_047293470.1  methyl-CpG-binding domain protein 1 isoform X7

  2. XM_017025776.3XP_016881265.1  methyl-CpG-binding domain protein 1 isoform X18

    UniProtKB/Swiss-Prot
    Q9UIS9
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  3. XM_047437519.1XP_047293475.1  methyl-CpG-binding domain protein 1 isoform X16

  4. XM_017025770.3XP_016881259.1  methyl-CpG-binding domain protein 1 isoform X15

    UniProtKB/Swiss-Prot
    Q9UIS9
    Related
    ENSP00000381506.1, ENST00000398493.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  5. XM_047437517.1XP_047293473.1  methyl-CpG-binding domain protein 1 isoform X10

  6. XM_047437513.1XP_047293469.1  methyl-CpG-binding domain protein 1 isoform X6

  7. XM_011526007.3XP_011524309.1  methyl-CpG-binding domain protein 1 isoform X13

    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  8. XM_047437516.1XP_047293472.1  methyl-CpG-binding domain protein 1 isoform X9

  9. XM_005258271.4XP_005258328.1  methyl-CpG-binding domain protein 1 isoform X5

    See identical proteins and their annotated locations for XP_005258328.1

    UniProtKB/Swiss-Prot
    Q9UIS9, Q9UNZ9
    Related
    ENSP00000467017.1, ENST00000591416.5
    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:331377
    zf-CXXC; CXXC zinc finger domain
  10. XM_047437518.1XP_047293474.1  methyl-CpG-binding domain protein 1 isoform X12

  11. XM_047437520.1XP_047293476.1  methyl-CpG-binding domain protein 1 isoform X17

  12. XM_047437515.1XP_047293471.1  methyl-CpG-binding domain protein 1 isoform X8

  13. XM_024451180.2XP_024306948.1  methyl-CpG-binding domain protein 1 isoform X14

    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:168215
    zf-CXXC; CXXC zinc finger domain
  14. XM_047437512.1XP_047293468.1  methyl-CpG-binding domain protein 1 isoform X4

  15. XM_047437510.1XP_047293466.1  methyl-CpG-binding domain protein 1 isoform X1

  16. XM_047437511.1XP_047293467.1  methyl-CpG-binding domain protein 1 isoform X2

  17. XM_011526002.3XP_011524304.1  methyl-CpG-binding domain protein 1 isoform X11

    See identical proteins and their annotated locations for XP_011524304.1

    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain
  18. XM_017025757.3XP_016881246.1  methyl-CpG-binding domain protein 1 isoform X3

    Conserved Domains (2) summary
    smart00391
    Location:376
    MBD; Methyl-CpG binding domain
    pfam02008
    Location:356402
    zf-CXXC; CXXC zinc finger domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    50468627..50483509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)