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BLID BH3-like motif containing, cell death inducer [ Homo sapiens (human) ]

Gene ID: 414899, updated on 25-Jan-2022

Summary

Official Symbol
BLIDprovided by HGNC
Official Full Name
BH3-like motif containing, cell death inducerprovided by HGNC
Primary source
HGNC:HGNC:33495
See related
Ensembl:ENSG00000259571 MIM:608853; AllianceGenome:HGNC:33495
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BRCC2
Summary
This gene encodes a BH3-like motif containing protein involved in cell death. The encoded protein may induce apoptosis in a caspase-dependent manner. The protein is localized in both the cytoplasm and the mitochondrion. [provided by RefSeq, Aug 2011]
Orthologs
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Genomic context

See BLID in Genome Data Viewer
Location:
11q24.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (122115340..122116215, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (121986048..121986923, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 256, pseudogene Neighboring gene mir-100-let-7a-2-mir-125b-1 cluster host gene Neighboring gene microRNA 125b-1 Neighboring gene microRNA let-7a-2 Neighboring gene microRNA 10526

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.
EBI GWAS Catalog
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC163233, MGC163235

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
BH3-like motif-containing cell death inducer
Names
breast cancer cell 2
breast cancer cell protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001786.3NP_001001786.2  BH3-like motif-containing cell death inducer

    See identical proteins and their annotated locations for NP_001001786.2

    Status: REVIEWED

    Source sequence(s)
    AF303179, AP001924, BC130363
    Consensus CDS
    CCDS31693.1
    UniProtKB/Swiss-Prot
    Q8IZY5
    Related
    ENSP00000453153.1, ENST00000560104.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    122115340..122116215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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