U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG9391 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40346, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CG9391provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037063
Locus tag
Dmel_CG9391
See related
AllianceGenome:FB:FBgn0037063
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
142335_at; Dmel\CG9391; IMP
Summary
Predicted to enable inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process; inositol phosphate dephosphorylation; and signal transduction. Predicted to be located in cytoplasm. Is expressed in Bolwig organ; adult head; adult heart; organism; and spermatozoon. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; bipolar disorder; intellectual disability; and schizophrenia. Orthologous to several human genes including IMPA2 (inositol monophosphatase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG9391 in Genome Data Viewer
Location:
78C3-78C3; 3-47 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21266680..21268335, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21259780..21261435, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ecdysone-induced protein 78C Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45162 Neighboring gene uncharacterized protein Neighboring gene Acetyl Coenzyme A synthase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. E2 ligase dRad6 regulates DMP53 turnover in Drosophila. Chen S, et al. J Biol Chem, 2011 Mar 18. PMID 21205821, Free PMC Article
  2. A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux. Allen EA, et al. J Cell Biol, 2020 Nov 2. PMID 32915229, Free PMC Article
  3. Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC). Borrás T, et al. Genetics, 2003 Feb. PMID 12618402, Free PMC Article
  4. Inferring gene function and network organization in Drosophila signaling by combined analysis of pleiotropy and epistasis. Carter GW. G3 (Bethesda), 2013 May 20. PMID 23550134, Free PMC Article
  5. Mating-responsive genes in reproductive tissues of female Drosophila melanogaster. Mack PD, et al. Proc Natl Acad Sci U S A, 2006 Jul 5. PMID 16798875, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables inositol monophosphate 1-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables inositol monophosphate 1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol monophosphate 1-phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in inositol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG9391-PA
CG9391-PC
NP_649294.1
NP_730610.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21266680..21268335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168893.3 → NP_730610.3  uncharacterized protein Dmel_CG9391, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730610.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KTW5
    Conserved Domains (1) summary
    cd01639
    Location:10 → 255
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

  2. NM_141037.5 → NP_649294.1  uncharacterized protein Dmel_CG9391, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649294.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KTW5
    Related
    FBpp0078071
    Conserved Domains (1) summary
    cd01639
    Location:10 → 255
    IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KTW5 Q7KTW5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous