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OR2A42 olfactory receptor family 2 subfamily A member 42 [ Homo sapiens (human) ]

Gene ID: 402317, updated on 11-Jun-2021

Summary

Official Symbol
OR2A42provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily A member 42provided by HGNC
Primary source
HGNC:HGNC:31230
See related
Ensembl:ENSG00000212807
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2A42 in Genome Data Viewer
Location:
7q35
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (144228244..144239605, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143925337..143936698, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 35 Neighboring gene ARHGEF35 antisense RNA 1 Neighboring gene uncharacterized LOC112267987 Neighboring gene OR2A1 antisense RNA 1 Neighboring gene olfactory receptor family 2 subfamily A member 20 pseudogene Neighboring gene Rho guanine nucleotide exchange factor 34, pseudogene Neighboring gene olfactory receptor family 2 subfamily A member 7

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2A1/2A42
Names
olfactory receptor OR7-16
olfactory receptor OR7-19
olfactory receptor, family 2, subfamily A, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001802.3NP_001001802.2  olfactory receptor 2A1/2A42

    See identical proteins and their annotated locations for NP_001001802.2

    Status: VALIDATED

    Source sequence(s)
    AC004889
    Consensus CDS
    CCDS56515.1
    UniProtKB/Swiss-Prot
    Q8NGT9
    Related
    ENSP00000493333.1, ENST00000641810.1
    Conserved Domains (2) summary
    pfam00001
    Location:40289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:30304
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    144228244..144239605 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_018654715.1 Reference GRCh38.p13 PATCHES

    Range
    182841..194199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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