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OR14I1 olfactory receptor family 14 subfamily I member 1 [ Homo sapiens (human) ]

Gene ID: 401994, updated on 22-Sep-2022

Summary

Official Symbol
OR14I1provided by HGNC
Official Full Name
olfactory receptor family 14 subfamily I member 1provided by HGNC
Primary source
HGNC:HGNC:19575
See related
Ensembl:ENSG00000189181 MIM:618516; AllianceGenome:HGNC:19575
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR5BU1; OR5BU1P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 1.0) and testis (RPKM 0.1) See more
Orthologs
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Genomic context

See OR14I1 in Genome Data Viewer
Location:
1q44
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (248678140..248699739, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (248116377..248123733, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248841441..248848789, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 35 Neighboring gene olfactory receptor family 2 subfamily T member 27 Neighboring gene LY6/PLAUR domain containing 9, pseudogene Neighboring gene adenosylhomocysteinase pseudogene 8 Neighboring gene uncharacterized LOC107985747 Neighboring gene LY6/PLAUR domain containing 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 14I1
Names
olfactory receptor 5BU1
olfactory receptor, family 5, subfamily BU, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004734.3NP_001004734.1  olfactory receptor 14I1

    See identical proteins and their annotated locations for NP_001004734.1

    Status: VALIDATED

    Source sequence(s)
    AC098483, AL672295, CR589904
    Consensus CDS
    CCDS31125.1
    UniProtKB/Swiss-Prot
    A6ND48, B2RNZ0
    Related
    ENSP00000339726.3, ENST00000342623.5
    Conserved Domains (2) summary
    pfam00001
    Location:39288
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    248678140..248699739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047420643.1XP_047276599.1  olfactory receptor 14I1 isoform X1

    UniProtKB/Swiss-Prot
    B2RNZ0

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791755.1 Reference GRCh38.p14 PATCHES

    Range
    319818..327178 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    248116377..248123733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)