U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR2T5 olfactory receptor family 2 subfamily T member 5 [ Homo sapiens (human) ]

Gene ID: 401993, updated on 10-Dec-2024

Summary

Official Symbol
OR2T5provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily T member 5provided by HGNC
Primary source
HGNC:HGNC:15017
See related
Ensembl:ENSG00000203661 AllianceGenome:HGNC:15017
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR1-62; OR2T29
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR2T5 in Genome Data Viewer
Location:
1q44
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (248488589..248491113)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247933309..247935837)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248651890..248654414)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr1:248616387-248616588 Neighboring gene olfactory receptor family 2 subfamily T member 2 Neighboring gene uncharacterized LOC105373279 Neighboring gene olfactory receptor family 2 subfamily T member 3 Neighboring gene uncharacterized LOC105373277 Neighboring gene olfactory receptor family 2 subfamily AS member 2 pseudogene Neighboring gene olfactory receptor family 2 subfamily G member 6

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 2T5
Names
olfactory receptor OR1-62

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004697.2NP_001004697.1  olfactory receptor 2T5

    See identical proteins and their annotated locations for NP_001004697.1

    Status: PROVISIONAL

    Source sequence(s)
    AC138089
    Consensus CDS
    CCDS31118.1
    UniProtKB/Swiss-Prot
    B9EIN2, Q6IEZ7
    UniProtKB/TrEMBL
    A0AAG2UVN0
    Related
    ENSP00000493066.1, ENST00000641363.1
    Conserved Domains (2) summary
    pfam00001
    Location:45294
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:38309
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    248488589..248491113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791755.1 Reference GRCh38.p14 PATCHES

    Range
    198887..201411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187518.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    142629..145153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187646.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    139007..141531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247933309..247935837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)