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IL17REL interleukin 17 receptor E like [ Homo sapiens (human) ]

Gene ID: 400935, updated on 23-Nov-2021

Summary

Official Symbol
IL17RELprovided by HGNC
Official Full Name
interleukin 17 receptor E likeprovided by HGNC
Primary source
HGNC:HGNC:33808
See related
Ensembl:ENSG00000188263 MIM:613414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See IL17REL in Genome Data Viewer
Location:
22q13.33
Exon count:
17
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (49991811..50013827, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (50430240..50451194, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985553 Neighboring gene cysteine rich with EGF like domains 2 Neighboring gene microRNA 6821 Neighboring gene Pim-3 proto-oncogene, serine/threonine kinase Neighboring gene tubulin tyrosine ligase like 8 Neighboring gene modulator of VRAC current 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).
GeneReviews: Not available
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
GeneReviews: Not available
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ41993

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables interleukin-17 receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative interleukin-17 receptor E-like
Names
IL-17 receptor E-like
IL-17RE-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001694.3NP_001001694.2  putative interleukin-17 receptor E-like isoform 1

    See identical proteins and their annotated locations for NP_001001694.2

    Status: VALIDATED

    Source sequence(s)
    AK123987, AL022327
    Consensus CDS
    CCDS33679.1
    UniProtKB/Swiss-Prot
    Q6ZVW7
    Related
    ENSP00000374633.2, ENST00000389983.6
    Conserved Domains (1) summary
    pfam15037
    Location:54294
    IL17_R_N; Interleukin-17 receptor extracellular region
  2. NM_001371416.1NP_001358345.1  putative interleukin-17 receptor E-like isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL022327
    Conserved Domains (1) summary
    pfam15037
    Location:111366
    IL17_R_N; Interleukin-17 receptor extracellular region
  3. NM_001371417.1NP_001358346.1  putative interleukin-17 receptor E-like isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL022327
    Conserved Domains (1) summary
    pfam15037
    Location:111461
    IL17_R_N; Interleukin-17 receptor extracellular region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    49991811..50013827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001755245.1 RNA Sequence

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