Format

Send to:

Choose Destination

FAM174B family with sequence similarity 174 member B [ Homo sapiens (human) ]

Gene ID: 400451, updated on 17-Jun-2019

Summary

Official Symbol
FAM174Bprovided by HGNC
Official Full Name
family with sequence similarity 174 member Bprovided by HGNC
Primary source
HGNC:HGNC:34339
See related
Ensembl:ENSG00000185442
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in prostate (RPKM 17.8), thyroid (RPKM 16.6) and 25 other tissues See more
Orthologs

Genomic context

See FAM174B in Genome Data Viewer
Location:
15q26.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (92617447..92734219, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (93160678..93199031, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene chromosome 15 open reading frame 32 Neighboring gene long intergenic non-protein coding RNA 930 Neighboring gene uncharacterized LOC105370975 Neighboring gene high mobility group nucleosome binding domain 1 pseudogene 38 Neighboring gene ribosomal protein L31 pseudogene 6 Neighboring gene H2A histone family member V pseudogene 1 Neighboring gene ferritin light chain pseudogene Neighboring gene uncharacterized LOC101926994

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population.
NHGRI GWA Catalog

General gene information

Markers

Homology

Clone Names

  • MGC102891

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207446.3NP_997329.2  membrane protein FAM174B precursor

    See identical proteins and their annotated locations for NP_997329.2

    Status: VALIDATED

    Source sequence(s)
    AC091544, BC060873
    Consensus CDS
    CCDS45355.1
    UniProtKB/Swiss-Prot
    Q3ZCQ3
    Related
    ENSP00000329040.5, ENST00000327355.6
    Conserved Domains (1) summary
    pfam06679
    Location:75158
    DUF1180; Protein of unknown function (DUF1180)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    92617447..92734219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_931814.3 RNA Sequence

  2. XR_001751273.1 RNA Sequence

  3. XR_931815.2 RNA Sequence

Support Center