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PATE4 prostate and testis expressed 4 [ Homo sapiens (human) ]

Gene ID: 399968, updated on 13-May-2022

Summary

Official Symbol
PATE4provided by HGNC
Official Full Name
prostate and testis expressed 4provided by HGNC
Primary source
HGNC:HGNC:35427
See related
Ensembl:ENSG00000237353 AllianceGenome:HGNC:35427
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PATE-B
Summary
Enables acetylcholine receptor regulator activity. Involved in regulation of neurotransmitter receptor activity. Located in acrosomal vesicle and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See PATE4 in Genome Data Viewer
Location:
11q24.2
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (125833316..125840072)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (125861917..125868678)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (125703211..125709967)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene prostate and testis expressed 2 Neighboring gene prostate and testis expressed 3 Neighboring gene uncharacterized LOC124902781 Neighboring gene HYLS1 centriolar and ciliogenesis associated Neighboring gene pseudouridine synthase 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • FLJ41047

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables acetylcholine receptor regulator activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of neurotransmitter receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
prostate and testis expressed protein 4
Names
PATE-like protein B
prostate and testis expression B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144874.1NP_001138346.1  prostate and testis expressed protein 4 precursor

    See identical proteins and their annotated locations for NP_001138346.1

    Status: VALIDATED

    Source sequence(s)
    AI674374, AK123042, AP000842, AW296313
    Consensus CDS
    CCDS44765.1
    UniProtKB/Swiss-Prot
    P0C8F1
    Related
    ENSP00000411439.2, ENST00000457514.3

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    125833316..125840072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    125861917..125868678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)