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C11orf87 chromosome 11 open reading frame 87 [ Homo sapiens (human) ]

Gene ID: 399947, updated on 25-Nov-2025
Official Symbol
C11orf87provided by HGNC
Official Full Name
chromosome 11 open reading frame 87provided by HGNC
Primary source
HGNC:HGNC:33788
See related
Ensembl:ENSG00000185742 AllianceGenome:HGNC:33788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NEURIM1; LOH11CR1A
Summary
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Restricted expression toward brain (RPKM 7.9) See more
Orthologs
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See C11orf87 in Genome Data Viewer
Location:
11q22.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (109422190..109429167)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (109432359..109439336)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (109292916..109299893)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 349 Neighboring gene uncharacterized LOC124900307 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:109261364-109261957 Neighboring gene chaperonin containing TCP1 subunit 6 pseudogene 5 Neighboring gene MPRA-validated peak1462 silencer Neighboring gene long intergenic non-protein coding RNA 2715

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes. Etemadikhah M, et al. Sci Rep, 2020 Jan 20. PMID 31959813, Free PMC Article
  2. Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers. Tran MTMT, et al. PLoS One, 2021. PMID 33886682, Free PMC Article
  3. Suppression of miR-147b contributed to H37Rv-infected macrophage viability and migration in tuberculosis in vitro. Niu J, et al. Microb Pathog, 2020 Jul. PMID 32179078
  4. Biological insights from 108 schizophrenia-associated genetic loci. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature, 2014 Jul 24. PMID 25056061, Free PMC Article
  5. The protein interaction landscape of the human CMGC kinase group. Varjosalo M, et al. Cell Rep, 2013 Apr 25. PMID 23602568

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers.
    Title: Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers.
  2. Suppression of miR-147b contributed to H37Rv-infected macrophage viability and migration in tuberculosis in vitro.
    Title: Suppression of miR-147b contributed to H37Rv-infected macrophage viability and migration in tuberculosis in vitro.
Submit: New GeneRIF Correction

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ33767

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein C11orf87
Names
neuronal integral membrane protein 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207645.4 → NP_997528.2  uncharacterized protein C11orf87 precursor

    See identical proteins and their annotated locations for NP_997528.2

    Status: VALIDATED

    Source sequence(s)
    AB096240, AK091086, AK303693, BC035798, DA221578, DA232989
    Consensus CDS
    CCDS31672.1
    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1
    Related
    ENSP00000331581.6, ENST00000327419.7
    Conserved Domains (1) summary
    pfam06365
    Location:56 → 100
    CD34_antigen; CD34/Podocalyxin family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    109422190..109429167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542818.3 → XP_011541120.1  uncharacterized protein C11orf87 isoform X2

    See identical proteins and their annotated locations for XP_011541120.1

    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1
    Related
    ENSP00000578022.1, ENST00000907963.1
    Conserved Domains (1) summary
    pfam06365
    Location:56 → 100
    CD34_antigen; CD34/Podocalyxin family

  2. XM_011542817.3 → XP_011541119.1  uncharacterized protein C11orf87 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    109432359..109439336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368764.1 → XP_054224739.1  uncharacterized protein C11orf87 isoform X2

    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1

  2. XM_054368763.1 → XP_054224738.1  uncharacterized protein C11orf87 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NUJ2.2 GenPept UniProtKB/Swiss-Prot:Q6NUJ2

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