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CCDC187 coiled-coil domain containing 187 [ Homo sapiens (human) ]

Gene ID: 399693, updated on 26-Oct-2022

Summary

Official Symbol
CCDC187provided by HGNC
Official Full Name
coiled-coil domain containing 187provided by HGNC
Primary source
HGNC:HGNC:30942
See related
Ensembl:ENSG00000260220 AllianceGenome:HGNC:30942
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 6.0), thyroid (RPKM 0.9) and 1 other tissue See more
Orthologs
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Genomic context

See CCDC187 in Genome Data Viewer
Location:
9q34.3
Exon count:
27
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136249973..136306901, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148479614..148536390, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139141819..139166855, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene LIM homeobox 3 Neighboring gene quiescin sulfhydryl oxidase 2 Neighboring gene 9q34.3 QSOX2 distal recombination region Neighboring gene uncharacterized LOC124902308 Neighboring gene uncharacterized LOC26102 Neighboring gene Sharpr-MPRA regulatory region 1004 Neighboring gene G protein signaling modulator 1 Neighboring gene Sharpr-MPRA regulatory region 3186

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC50722

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in microtubule anchoring IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 187

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291516.1NP_001278445.1  coiled-coil domain-containing protein 187 isoform 1

    Status: VALIDATED

    Source sequence(s)
    FP326719
    Consensus CDS
    CCDS78462.1
    UniProtKB/TrEMBL
    A0A075B733
    Related
    ENSP00000456543.1, ENST00000569961.5
  2. NM_001378188.1NP_001365117.1  coiled-coil domain-containing protein 187 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CR392000, FP326719
    Consensus CDS
    CCDS94533.1
    UniProtKB/TrEMBL
    A0A1W2PQX5
    Related
    ENSP00000492326.1, ENST00000638797.2
    Conserved Domains (3) summary
    PHA03247
    Location:13481948
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:13161526
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    NF033201
    Location:12341379
    Vip_LPXTG_Lm; cell invasion LPXTG protein Vip

RNA

  1. NR_111982.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    FP326719
    Related
    ENST00000563590.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    136249973..136306901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047423386.1XP_047279342.1  coiled-coil domain-containing protein 187 isoform X10

  2. XM_047423384.1XP_047279340.1  coiled-coil domain-containing protein 187 isoform X8

  3. XM_047423385.1XP_047279341.1  coiled-coil domain-containing protein 187 isoform X9

  4. XM_047423383.1XP_047279339.1  coiled-coil domain-containing protein 187 isoform X7

  5. XM_047423382.1XP_047279338.1  coiled-coil domain-containing protein 187 isoform X6

  6. XM_047423380.1XP_047279336.1  coiled-coil domain-containing protein 187 isoform X4

  7. XM_047423381.1XP_047279337.1  coiled-coil domain-containing protein 187 isoform X5

  8. XM_047423379.1XP_047279335.1  coiled-coil domain-containing protein 187 isoform X3

  9. XM_047423388.1XP_047279344.1  coiled-coil domain-containing protein 187 isoform X12

  10. XM_047423387.1XP_047279343.1  coiled-coil domain-containing protein 187 isoform X11

  11. XM_047423378.1XP_047279334.1  coiled-coil domain-containing protein 187 isoform X2

  12. XM_047423377.1XP_047279333.1  coiled-coil domain-containing protein 187 isoform X1

  13. XM_047423389.1XP_047279345.1  coiled-coil domain-containing protein 187 isoform X13

  14. XM_011518681.3XP_011516983.1  coiled-coil domain-containing protein 187 isoform X14

RNA

  1. XR_007061299.1 RNA Sequence

  2. XR_007061300.1 RNA Sequence

  3. XR_929795.3 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    148479614..148536390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001378118.1: Suppressed sequence

    Description
    NM_001378118.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.