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sap18 Sin3A-associated protein [ Danio rerio (zebrafish) ]

Gene ID: 393693, updated on 27-Mar-2024

Summary

Official Symbol
sap18provided by ZNC
Official Full Name
Sin3A-associated proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1679
See related
Ensembl:ENSDARG00000057854 AllianceGenome:ZFIN:ZDB-GENE-040426-1679
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73118
Summary
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human SAP18 (Sin3A associated protein 18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See sap18 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (21266684..21268601, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (21455815..21457732, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene hyperpolarization activated cyclic nucleotide-gated potassium channel 5 Neighboring gene spindle and kinetochore associated complex subunit 3 Neighboring gene uncharacterized LOC101884374 Neighboring gene large tumor suppressor kinase 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC73118

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
enables transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
histone deacetylase complex subunit SAP18
Names
sin3-associated polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200720.2NP_957014.1  histone deacetylase complex subunit SAP18

    See identical proteins and their annotated locations for NP_957014.1

    Status: VALIDATED

    Source sequence(s)
    BI709589, BX511129, EH440312
    UniProtKB/TrEMBL
    A9JT48, Q6PC41
    Related
    ENSDARP00000075051.5, ENSDART00000080604.6
    Conserved Domains (1) summary
    pfam06487
    Location:24137
    SAP18; Sin3 associated polypeptide p18 (SAP18)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    21266684..21268601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394749.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    136443..138358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)